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Merck

1366002

USP

Lidocaine

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

2-Diethylamino-N-(2,6-dimethylphenyl)acetamide, Lignocaine, Xylocaine

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About This Item

Empirical Formula (Hill Notation):
C14H22N2O
CAS Number:
137-58-6
Molecular Weight:
234.34
NACRES:
NA.24
PubChem Substance ID:
329750054
UNSPSC Code:
41116107
MDL number:
MFCD00026733

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InChI

1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)

SMILES string

CCN(CC)CC(=O)Nc1c(C)cccc1C

InChI key

NNJVILVZKWQKPM-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

lidocaine

manufacturer/tradename

USP

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Lidocaine USP reference standard for use in specified quality tests and assays.

Also used to prepare standard and system suitability solution for assay, identification and impurity analysis according to given below monographs of the United States Pharmacopeia (USP):
  • Lidocaine
  • Lidocaine Hydrochloride Topical Solution
  • Lidocaine Hydrochloride Oral Topical Solution
  • Lidocaine Hydrochloride Jelly

Biochem/physiol Actions

Na+ channel blocker; class IB antiarrhythmic that is rapidly absorbed after parenteral administration.
Na+ channel blocker; class IB antiarrhythmic.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

1366002-250MG:

jan

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Certificates of Analysis (COA)

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Lidocaine Hydrochloride Oral Topical Solution
United States Pharmacopeia, 44(4), 2626-2626 (2020)
Lidocaine Hydrochloride Jelly
United States Pharmacopeia, 43(6), 2625-2625 (2020)
Lidocaine
United States Pharmacopeia, 43(3), 2620-2620 (2020)
Corrine A Nief et al.
Cancers, 14(19) (2022-10-15)
Ethanol ablation is a minimally invasive, cost-effective method of destroying tumor tissue through an intratumoral injection of high concentrations of cytotoxic alcohol. Ethyl-cellulose ethanol (ECE) ablation, a modified version of ethanol ablation, contains the phase-changing polysaccharide ethyl-cellulose to reduce ethanol
Lidocaine Hydrochloride Topical Solution
United States Pharmacopeia, 44(4), 2627-2627 (2020)
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