9HTEo- Human Tracheal Epithelial Cell Line

9HTEo- is a human tracheal epithelial cell line that was immortalized with the origin-of-replication defective SV40 plasmid (pSVori-). The cell line retains characteristic features of normal differentiated tracheal epithelial cells including a cobblestone morphology, cytokeratin expression and the ability to form tight junctions.

9HTEo- cells contain the wild-type cystic fibrosis transmembrane conductance regulator (WT-CFTR) and exhibits functional cAMP-dependent chloride ion transport and calcium ion-dependent chloride transport (1,2).

9HTEo- is a useful model for the study of epithelial ion transport, secretion and biochemistry and frequently used as a wild-type control for human CF tracheobronchial epithelial cells such as CFBE41o- (Cat. No. SCC151) and CFTE29o- (Cat. No. SCC162).

Subject to local law, this product is intended to be sold for internal in vitro research use only subject to terms and conditions found here: www.sigmaaldrich.com/restrictedcelluse. This product may not be: re-engineered or copied; used to make derivatives, modifications or functional equivalents; used to obtain patents or other IP claiming use of the product; used to develop, test, or manufacturer a commercial product; used as a component in a commercial product; resold or licensed; used in any clinical applications or trials; or used in humans. A license or limited commercial use agreement is required for use by any for-profit entity, use in services, and use in sponsored academic research. For information regarding any such use, please contact licensing@milliporesigma.com.

Each vial contains more than 1X10⁶ viable cells.

This product contains genetically modified organisms (GMO). Within the EU GMOs are regulated by Directives 2001/18/EC and 2009/41/EC of the European Parliament and of the Council and their national implementation in the member States respectively. This legislation obliges {HCompany} to request certain information about you and the establishment where the GMOs are being handled. Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.