MAB2057
Anti-Integrin α3 Antibody, clone ASC-6
clone ASC-6, Chemicon®, from mouse
別名:
CD49c
製品名
Anti-Integrin α3 Antibody, clone ASC-6, clone ASC-6, Chemicon®, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
ASC-6, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ITGA3(3675)
関連するカテゴリー
Application
Anti-Integrin α3 Antibody, clone ASC-6 is an antibody against Integrin α3 for use in FC, IP, IH.
Inhibition of cell attachment: inhibits SCC9 cell adhesion to human and EHS laminin, but not laminin peptide GD-2. Potentiates inhibition of SKOV-3 cell adhesion to EHS laminin by anti-integrin alpha 5 antibody GoH3. Does not inhibit either cell′s adhesion to fibronectin or collagen type IV.
Immunohistochemistry: on acetone-fixed frozen human epithelial tissues including tongue,foreskin and ovary. Not for use on formalin-fixed tissue.
Flow cytometry: stains human squamous cell carcinoma (SCC9), ovarian carcinoma (SKOV-3) and umbilical vein endothelial cells (HUVEC).
Working dilutions must be determined by end user.
Immunohistochemistry: on acetone-fixed frozen human epithelial tissues including tongue,foreskin and ovary. Not for use on formalin-fixed tissue.
Flow cytometry: stains human squamous cell carcinoma (SCC9), ovarian carcinoma (SKOV-3) and umbilical vein endothelial cells (HUVEC).
Working dilutions must be determined by end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Integrins
Integrins
Biochem/physiol Actions
Human alpha3 integrin (CD49c)
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
Human squamous cell carcinoma cells (SCC9)
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Format: Purified
Liquid in 0.02M PB pH 7.6, 0.25M NaCl containing 0.1% sodium azide.
Preparation Note
Maintain at 2-8°C in undiluted aliquots for up to 6 months.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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保管分類
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Yi I Wu et al.
The Biochemical journal, 407(2), 171-177 (2007-07-26)
The transmembrane collagenase MT1-MMP (membrane-type 1 matrix metalloproteinase), also known as MMP-14, has a critical function both in normal development and in cancer progression, and is subject to extensive controls at the post-translational level which affect proteinase activity. As zymogen
Yu-Chen Gu et al.
Blood, 101(3), 877-885 (2002-10-24)
Laminins are alphabetagamma heterotrimeric extracellular proteins that regulate cellular functions by adhesion to integrin and nonintegrin receptors. Laminins containing alpha4 and alpha5 chains are expressed in bone marrow, but their interactions with hematopoietic progenitors are unknown. We studied human bone
Andrey Makarov et al.
Cell biology international, 37(10), 1080-1088 (2013-05-21)
Glioblastoma is the most common brain cancer. Ephrins and their Eph receptors play important roles in the development of central nervous system and the regulation of cancer cell migration and invasion. In a search for the Eph receptor complexes, we
Michelle B Chen et al.
Cancer research, 76(9), 2513-2524 (2016-03-19)
Tumor integrin β1 (ITGB1) contributes to primary tumor growth and metastasis, but its specific roles in extravasation have not yet been clearly elucidated. In this study, we engineered a three-dimensional microfluidic model of the human microvasculature to recapitulate the environment
Beta1 integrin mediates internalization of mammalian reovirus.
Maginnis, MS; Forrest, JC; Kopecky-Bromberg, SA; Dickeson, SK; Santoro, SA; Zutter et al.
Journal of virology null
グローバルトレードアイテム番号
| カタログ番号 | GTIN |
|---|---|
| MAB2057 | 04053252501883 |
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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