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Merck

1.00804

L(+)-Tartaric acid

for analysis EMSURE® ACS,ISO,Reag. Ph Eur

別名:

L(+)-Tartaric acid, 2,3-Dihydroxybutanedioic acid

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この商品について

化学式:
HOOCCH(OH)CH(OH)COOH
CAS番号:
分子量:
150.09
UNSPSC Code:
12352106
EC Index Number:
201-766-0
NACRES:
NA.21
MDL number:
Assay:
≥99.5-101.0% dry basis (alkalimetric)
Form:
solid
Grade:
ACS reagent
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grade

ACS reagent

Quality Segment

agency

reag. ISO, reag. Ph. Eur., suitable for EPA 200.7, suitable for EPA 200.8

vapor pressure

<5 Pa ( 20 °C)

product line

EMSURE®

assay

≥99.5-101.0% dry basis (alkalimetric)

form

solid

autoignition temp.

425 °C

impurities

≤10 ppm Phosphate (PO4), ≤100 ppm Sulfated ash, ≤20 ppm Total sulfur (as SO4), ≤350 ppm Oxalic acid, ≤5 ppm Chloride (Cl), ≤50 ppm Insoluble matter, ≤50 ppm Sulfate (SO4)

loss

≤ 0.2% loss on drying, 105°C

pH

1.6 (25 °C, 100 g/L in H2O)

mp

168-170 °C

transition temp

flash point 210 °C

solubility

water: 1390 g/L at 20 °C

density

1.76 g/cm3 at 20 °C

bulk density

1000 kg/m3

cation traces

Ca: ≤20 ppm, Cu: ≤5 ppm, Fe: ≤5 ppm, Pb: ≤5 ppm, heavy metals (as Pb): ≤5 ppm

storage temp.

2-30°C

SMILES string

[O-]C(=O)C(O)C(O)C(=O)[O-].[H+].[H+]

InChI

1S/C4H6O6/c5-1(3(7)8)2(6)4(9)10/h1-2,5-6H,(H,7,8)(H,9,10)

InChI key

FEWJPZIEWOKRBE-UHFFFAOYSA-N

Application


  • Binary Mixtures of Meloxicam and L-Tartaric Acid for Oral Bioavailability Modulation of Pharmaceutical Dosage Forms.: This study explores the use of L(+)-tartaric acid in binary mixtures to enhance the oral bioavailability of meloxicam, suggesting potential applications in developing more effective pharmaceutical formulations (Macasoi et al., 2024).

  • Hyper-Raman spectroscopy of biomolecules.: This research employs Hyper-Raman spectroscopy, an analytical technique enhanced by L(+)-tartaric acid, to provide insights into the structural dynamics of biomolecules, showcasing its utility in complex biological systems (Marble et al., 2024).

  • Novel multi-component crystals of berberine with improved pharmaceutical properties.: This study highlights the use of L(+)-tartaric acid in the development of novel multi-component crystals, potentially leading to pharmaceuticals with enhanced efficacy and stability (Zhang et al., 2023).

  • Deep Eutectic Solvent (DES)-Mediated One-Pot Multicomponent Green Approach for Naphthalimide-Centered Acridine-1,8-dione Derivatives and Their Photophysical Properties.: Research demonstrates the synthesis of complex organic compounds using L(+)-tartaric acid as a component of a deep eutectic solvent, highlighting its role in green chemistry (Rather et al., 2022).

Analysis Note

Assay (alkalimetric): ≥ 99.5 %
Assay (alkalimetric, calculated on dried substance): 99.5 - 101.0 %
Identity: passes test
Appearance of solution: passes test
Insoluble matter: ≤ 50 ppm
Spec. rotation [α²0/D (20 %; water calculated on dried substance): 12.0 - 12.8 °
Chloride (Cl): ≤ 5 ppm
Phosphate (PO₄): ≤ 10 ppm
Sulfate (SO₄): ≤ 50 ppm
Heavy metals (as Pb): ≤ 5 ppm
Total sulfur (as SO₄): ≤ 20 ppm
Ca (Calcium): ≤ 20 ppm
Cu (Copper): ≤ 5 ppm
Fe (Iron): ≤ 5 ppm
Pb (Lead): ≤ 5 ppm
Oxalate (C₂O₄): passes test
Oxalic acid: ≤ 350 ppm
Sulfated ash: ≤ 100 ppm
Loss on Drying (105°C): ≤ 0.2 %
Corresponds to ACS,ISO,Reag. Ph Eur

Other Notes

Replaces: TX0010-1; TX0010

Legal Information

EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany


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pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1

保管分類

11 - Combustible Solids

wgk

WGK 1

flash_point_f

302.0 °F - closed cup

flash_point_c

150 °C - closed cup



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