1.06525
Sodium iodate
for analysis EMSURE®
別名:
Sodium iodate
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この商品について
実験式（ヒル表記法）:
INaO3
CAS番号:
分子量:
197.89
UNSPSC Code:
12352302
EC Index Number:
231-672-5
NACRES:
NA.21
MDL number:
Assay:
≥99.5% (iodometric)
Form:
solid
Solubility:
81 g/L
Quality Segment
product line
EMSURE®
assay
≥99.5% (iodometric)
form
solid
pH
5.8 (25 °C, 90 g/L in H2O)
solubility
81 g/L
density
4.28 g/cm3 at 20 °C
bulk density
1150 kg/m3
anion traces
bromide, bromate, chloride, chlorate (as Cl-): ≤0.02%, iodide (I-): ≤0.002%, sulfate (SO42-): ≤0.005%
cation traces
Cd: ≤0.00005%, Cu: ≤0.0001%, Fe: ≤0.001%, K: ≤0.02%, Mn: ≤0.00005%, N: ≤0.002%, Pb: ≤0.0002%, Zn: ≤0.0001%
storage temp.
2-30°C
SMILES string
[Na+].[I](=O)(=O)[O-]
InChI
1S/HIO3.Na/c2-1(3)4;/h(H,2,3,4);/q;+1/p-1
InChI key
WTCBONOLBHEDIL-UHFFFAOYSA-M
Application
- Comparative Analysis of Molecular Landscape in Mouse Models and Patients Reveals Conserved Inflammation Pathways in Age-Related Macular Degeneration.: This study highlights the use of sodium iodate to induce retinal degeneration in mouse models to explore conserved inflammation pathways relevant to age-related macular degeneration. This model provides insights into potential therapeutic targets for inflammatory diseases of the retina (Liu et al., 2024).
- The BET PROTAC inhibitor dBET6 protects against retinal degeneration and inhibits the cGAS-STING in response to light damage.: Sodium iodate was utilized to model retinal degeneration, showing the effectiveness of the BET PROTAC inhibitor dBET6 in protecting against retinal damage and modulating inflammatory responses, potentially offering new treatment avenues for retinal diseases (Zhu et al., 2023).
- Sodium Iodate-Induced Degeneration Results in Local Complement Changes and Inflammatory Processes in Murine Retina.: This research delves into the specific inflammatory processes and complement system changes following sodium iodate-induced retinal degeneration in mice, providing a detailed molecular understanding of retinal inflammatory responses (Enzbrenner et al., 2021).
- IL-33trap-mediated IL-33 neutralization does not exacerbate choroidal neovascularization, but fails to protect against retinal degeneration in a dry age-related macular degeneration model.: The study used sodium iodate to induce retinal degeneration and test IL-33 neutralization′s effectiveness in preventing retinal damage, contributing to the understanding of inflammatory pathways in retinal diseases (Van Hove et al., 2021).
- An Acute Injury Model for the Phenotypic Characteristics of Geographic Atrophy.: Utilizing sodium iodate to create an acute retinal injury model, this study mimics the phenotypic characteristics of geographic atrophy, providing a valuable tool for studying this condition and testing potential treatments (Bhutto et al., 2018).
Analysis Note
Assay (iodometric): ≥ 99.5 %
pH-value (5 %; water): 5 - 8
Chloride, Chlorate, Bromide, Bromate (as Cl): ≤ 0.02 %
Iodide (I): ≤ 0.002 %
Sulfate (SO₄): ≤ 0.005 %
Total nitrogen (N): ≤ 0.002 %
Cd (Cadmium): ≤ 0.00005 %
Cu (Copper): ≤ 0.0001 %
Fe (Iron): ≤ 0.001 %
K (Potassium): ≤ 0.02 %
Mn (Manganese): ≤ 0.00005 %
Pb (Lead): ≤ 0.0002 %
Zn (Zinc): ≤ 0.0001 %
pH-value (5 %; water): 5 - 8
Chloride, Chlorate, Bromide, Bromate (as Cl): ≤ 0.02 %
Iodide (I): ≤ 0.002 %
Sulfate (SO₄): ≤ 0.005 %
Total nitrogen (N): ≤ 0.002 %
Cd (Cadmium): ≤ 0.00005 %
Cu (Copper): ≤ 0.0001 %
Fe (Iron): ≤ 0.001 %
K (Potassium): ≤ 0.02 %
Mn (Manganese): ≤ 0.00005 %
Pb (Lead): ≤ 0.0002 %
Zn (Zinc): ≤ 0.0001 %
Legal Information
EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany
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注意喚起語
Danger
保管分類
5.1B - Oxidizing hazardous materials
一体何が起きているの？
WGK 1
引火点 (F)
Not applicable
引火点（°C）
Not applicable
ハザードコード
Hazard Classifications
Acute Tox. 4 Oral - Ox. Sol. 2 - Skin Sens. 1
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Substances Subject to be Indicated Names
ishl_indicated
Substances Subject to be Notified Names
ishl_notified
Group 1: Oxidizing solids + Iodates + Hazardous rank I + 1st oxidizing solid
fsl
1065250100: + 1065250000: + 1065251000:
jan