1.11474
1,4-Dithiothreitol
for biochemistry
別名:
1,4-Dithiothreitol, DTT, Cleland’s reagent
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この商品について
化学式:
(C2H3OHSH)2
CAS番号:
分子量:
154.25
UNSPSC Code:
12352104
EC Index Number:
222-468-7
NACRES:
NB.21
MDL number:
Assay:
≥99% (iodometric)
Form:
solid
Quality Segment
assay
≥99% (iodometric)
form
solid
potency
400 mg/kg LD50, oral (Rat)
reaction suitability
reagent type: reductant
pH
5.1 (20 °C, 10 g/L in H2O)
mp
40-43 °C
transition temp
flash point >110 °C
bulk density
300 kg/m3
storage temp.
2-8°C
SMILES string
SC[C@H](O)[C@@H](O)CS
InChI
1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m0/s1
InChI key
VHJLVAABSRFDPM-IMJSIDKUSA-N
Application
- Drug delivery using reduction-responsive hydrogel based on carboxyethyl-succinoglycan with highly improved rheological, antibacterial, and antioxidant properties.: This study explores the application of 1,4-Dithiothreitol in developing reduction-responsive hydrogels, highlighting significant enhancements in rheological, antibacterial, and antioxidant characteristics, suitable for drug delivery systems (Kim et al., 2024).
- Preparation and properties of hydrogel photonic crystals assembled by biodegradable nanogels.: Research discusses the integration of 1,4-Dithiothreitol in the assembly of hydrogel photonic crystals using biodegradable nanogels, emphasizing their potential in creating novel photonic materials (Zhang et al., 2024).
- Optimized total RNA isolation from bovine sperm with enhanced sperm head lysis.: The paper highlights the use of 1,4-Dithiothreitol in optimizing RNA isolation techniques from bovine sperm, which enhances sperm head lysis, crucial for reproductive biology studies (Tiwari et al., 2024).
- Preparation of a Convertible Spacer Containing a Disulfide Group for Versatile Functionalization of Oligonucleotides.: Discusses the synthesis of a convertible spacer containing a disulfide group using 1,4-Dithiothreitol, enabling versatile functionalization of oligonucleotides for therapeutic and diagnostic applications (Pontarelli et al., 2023).
Analysis Note
Assay (iodometric): ≥ 99 %
Identity (IR-spectrum): passes test
Melting point: 40 - 43 °C
Heavy metals (as Pb): ≤ 10 ppm
Fe (Iron): ≤ 5 ppm
Identity (IR-spectrum): passes test
Melting point: 40 - 43 °C
Heavy metals (as Pb): ≤ 10 ppm
Fe (Iron): ≤ 5 ppm
signalword
Danger
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1B
保管分類
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
hcodes
適用法令
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1114740025: + 1114740001: + 1114749999: + 1114740005: + 1114740000: + 1114740500: + 1114748888:
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