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171601

Amyloid Precursor Protein β-Secretase Inhibitor

Name: Amyloid Precursor Protein β-Secretase Inhibitor
Brand: MM

The Amyloid Precursor Protein β-Secretase Inhibitor controls the biological activity of Amyloid Precursor Protein β-Secretase. This small molecule/inhibitor is primarily used for Neuroscience applications.

別名:

Amyloid Precursor Protein β-Secretase Inhibitor, KTEETSEVN(stat)VAEF

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この商品について

実験式（ヒル表記法）:

C₇₃H₁₁₈N₁₆O₂₇

分子量:

1651.81

NACRES:

NA.77

UNSPSC Code:

12352202

Assay:

≥98% (HPLC)

Form:

lyophilized

Storage condition:

OK to freeze, desiccated (hygroscopic)

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特性

Quality Segment

100

assay

≥98% (HPLC)

form

lyophilized

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, desiccated (hygroscopic)

solubility

aqueous buffer, pH 7.5: 1 mg/mL

shipped in

ambient

storage temp.

−20°C

詳細

General description

A potent inhibitor of the amyloid precursor protein (APP) β-secretase (IC₅₀ = 30 nM).

Biochem/physiol Actions

Reversible: no

Target IC₅₀: 30 nM against amyloid precursor protein (APP) β-secretase

Cell permeable: no

Primary Target
APP

Product does not compete with ATP.

Physical form

Supplied as a trifluoroacetate salt.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

H-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Stat-Val-Ala-Glu-Phe-OH [Stat = (3S,4S)-Statine]

Sinha, S., et al. 1999. Nature 402, 537.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

保管分類

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c