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この商品について
実験式(ヒル表記法):
C78H142N22O20
分子量:
1708.10
UNSPSC Code:
12352202
NACRES:
NA.77
Assay:
≥97% (HPLC)
Form:
lyophilized
Storage condition:
OK to freeze, desiccated (hygroscopic)
製品名
Autocamtide-2 Related Inhibitory Peptide, Myristoylated, The Autocamtide-2 Related Inhibitory Peptide, Myristoylated controls the biological activity of calmodulin-dependent protein kinase II. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
Quality Segment
assay
≥97% (HPLC)
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic)
solubility
water: 1 mg/mL
shipped in
ambient
storage temp.
−20°C
General description
This peptide corresponds to AIP (Cat. No. 189480 ) which has been myristoylated at the N-terminus, thus enhancing its cell-permeability.
Biochem/physiol Actions
Cell permeable: yes
Primary Target
Calmodulin-Dependent Protein Kinase (CaM Kinase)-2
Calmodulin-Dependent Protein Kinase (CaM Kinase)-2
Product does not compete with ATP.
Reversible: no
Target IC50: 40 nM against cam Kinase-2
Physical form
Supplied as a trifluoroacetate salt.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Gailly, P., et al. 1998. Cell Calcium 24, 293.
Ishida, A., and Fujisawa, H. 1995. J. Biol. Chem.270, 2163.
Ishida, A., et al. 1995. Biochem. Biophys. Res. Commun.212, 806.
Ishida, A., and Fujisawa, H. 1995. J. Biol. Chem.270, 2163.
Ishida, A., et al. 1995. Biochem. Biophys. Res. Commun.212, 806.
Myr-N-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
保管分類
11 - Combustible Solids
WGK
WGK 1
引火点 (F)
Not applicable
引火点(°C)
Not applicable