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204902

Complement C5a des-Arg, Human

Name: Complement C5a des-Arg, Human
Brand: MM

Complement C5a des-Arg, Human, is a native, single chain glycopeptide (73 aa). Once produced, C5a is converted to C5a des-Arg upon removal of the C-terminal arginine by serum carboxypeptidase N.

別名:

C5a Complement

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この商品について

NACRES:

NA.25

UNSPSC Code:

12352202

Form:

liquid

Assay:

≥90% (SDS-PAGE)

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特性

Quality Level

100

assay

≥90% (SDS-PAGE)

form

liquid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

shipped in

wet ice

storage temp.

−70°C

詳細

General description

Native, human des-Arg C5a complement component. Single chain glycopeptide composed of 73 amino acids. Once the C5a glycopeptide has been produced in human plasma or serum, it is rapidly converted to C5a des-Arg upon removal of the C-terminal arginine by the endogenous serum carboxypeptidase N. Unlike the C3a des-Arg peptide, C5a des-Arg retains significant levels of its biological activities. Thus, C5a des-Arg has been shown to exhibit inflammatory cell chemotaxis, smooth muscle contraction, and leukotriene release from guinea pig lung.

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In 120 mM NaCl, 10 mM HEPES, pH 7.2.

Preparation Note

Following initial thaw, aliquot and freeze (-70°C).

Prepared from plasma of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Other Notes

Webster, R.O., et al. 1980. Immunopharmacology 1, 201.
McCarthy, K. and Henson, P.M. 1979. J. Immunol. 123, 2511.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

保管分類

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c