218753
Caspase-5 Inhibitor I
Single spot by TLC, solid, Caspase-5 inhibitor, Calbiochem®
別名:
Caspase-5 Inhibitor I, Z-WE(OMe)HD(OMe)-FMK
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この商品について
実験式（ヒル表記法）:
C37H42FN7O10
分子量:
763.77
UNSPSC Code:
12352200
NACRES:
NA.77
eCl@ss:
32150313
Form:
solid
Storage condition:
OK to freeze, desiccated
製品名
Caspase-5 Inhibitor I, Z-WEHD-FMK is a cell-permeable, potent, irreversible caspase-5 inhibitor, that also inhibits the activity of Caspase 1, 4, and 8.
Quality Segment
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated
color
white
solubility
DMSO: 5 mg/mL
shipped in
ambient
storage temp.
−20°C
General description
A potent, cell-permeable and irreversible inhibitor of caspase-5 (ICErel-III, TY), as well as caspase-1 and caspase-4.
A potent, cell-permeable, and irreversible inhibitor of caspase-5. Strongly inhibits caspase-1. Also inhibits caspase-4 and caspase-8.
Biochem/physiol Actions
Primary Target
caspase-1, caspase-4, caspase-5, caspase-8
caspase-1, caspase-4, caspase-5, caspase-8
Reversible: no
Cell permeable: yes
Physical form
Supplied as a trifluoroacetate salt.
Preparation Note
Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.
Analysis Note
single spot by TLC
Other Notes
Garcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Rano, T., et al. 1997. Chem. Biol. 4, 149.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Rano, T., et al. 1997. Chem. Biol. 4, 149.
Z-Trp-Glu(OMe)-His-Asp(OMe)-CH₂F*
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
保管分類
11 - Combustible Solids
WGK
WGK 1
引火点 (F)
Not applicable
引火点（°C）
Not applicable