219399
Cathepsin D Substrate I
Useful as a substrate for the determination of cathepsin D activity.
別名:
Cathepsin D Substrate I, Bz-RGFFP-4-MeOβNA, HCl
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この商品について
実験式（ヒル表記法）:
C49H55N9O7 · xHCl
分子量:
882.02 (free base basis)
NACRES:
NA.77
UNSPSC Code:
51111800
Assay:
≥95% (HPLC)
Form:
lyophilized solid
Storage condition:
OK to freeze, desiccated, protect from light
Quality Segment
assay
≥95% (HPLC)
form
lyophilized solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated, protect from light
color
white
solubility
DMSO: 5 mg/mL
fluorescence
λex ~345 nm, λem ~425 nm
shipped in
ambient
storage temp.
−20°C
General description
A useful substrate for colorimetric or fluorometric assay of cathepsin D activity. Cathepsin D hydrolyzes the Phe-Phe bond. Dipeptidyl aminopeptidase II is required to free the 4-methoxy-β-naphthylamine (4MβNA). Excitation max: ~345 nm; emission max: ~425 nm.
Useful as a substrate for the determination of cathepsin D activity. Suitable for either colorimetric or fluorometric assay. Cathepsin D hydrolyzes the Phe-Phe bond. Requires dipeptidyl aminopeptidase II to free 4-methoxy-β-naphthylamine (4MeOβNA).
Biochem/physiol Actions
Cell permeable: no
Primary Target
Substrate for the determination of cathepsin D activity
Substrate for the determination of cathepsin D activity
Product does not compete with ATP.
Reversible: no
Other Notes
Bz-Arg-Gly-Phe-Phe-Pro-4MeOβNA, HCl
Takahashi, T., and Tang, J. 1981. Methods Enzymol.80, 565.
Smith, R.E., and Van Frank, R.M. 1975. in Lysosomes in Biology and Pathology4 (Dingle, J.T., and Dean, R.T., eds.) p. 193, American Elsevier, Holland.
Smith, R.E., and Van Frank, R.M. 1975. in Lysosomes in Biology and Pathology4 (Dingle, J.T., and Dean, R.T., eds.) p. 193, American Elsevier, Holland.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
保管分類
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
試験成績書（COA）
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