220411
Chenodeoxycholic Acid, Sodium Salt
Bile acid that has been shown to increase intracellular Ca2+ in isolated rat hepatocyte couplets. Induces a permeability transition in freshly isolated rat liver mitochondria.
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Chenodeoxycholic Acid, Sodium Salt
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Quality Segment
description
Merck USA index - 14, 2054
assay
>95% (TLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic)
color
white
solubility
water: 20 mg/mL, aqueous buffer: soluble
cation traces
heavy metals: <10 ppm
shipped in
ambient
storage temp.
15-25°C
SMILES string
[Na+].[O-]C(=O)CC[C@H]([C@@H]1[C@@]2([C@H]([C@H]3[C@@H]([C@@]4([C@H](C[C@H]3O)C[C@@H](CC4)O)C)CC2)CC1)C)C
InChI
1S/C24H40O4.Na/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26;/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-;/m1./s1
InChI key
WDFRNBJHDMUMBL-OICFXQLMSA-M
General description
Other Notes
Thibault, N., and Ballet, F. 1993. Biochem. Pharmacol. 45, 289.
Roda, A., et al. 1990. J. Lipid Res.31, 1433.
Spivak, W., et al. 1988. Biochem. J.252, 275.
Hisadome, T., et al. 1980. Gastroenterol. Jpn.15, 257.
Legal Information
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Hazard Classifications
Acute Tox. 3 Oral - Repr. 2
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6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
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WGK 3
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Not applicable
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Not applicable
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