251700
1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride
UPA inhibitor, solid
別名:
1,5-DNS-GGACK, 2HCl
ログインで組織・契約価格をご覧ください。
サイズを選択してください
表示を変更する
この商品について
UNSPSC Code:
12352200
NACRES:
NA.77
eCl@ss:
32150312
Form:
solid
Storage condition:
OK to freeze, desiccated
製品名
1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride, Effective irreversible inhibitor of uPA, Factor Xa, and urokinase.
Quality Segment
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated
color
off-white
solubility
soluble (Reconstitute at 1 mg/ml in 10 mM HCl. Dilute with physiological buffers just prior to use.)
shipped in
ambient
storage temp.
2-8°C
General description
Effective irreversible inhibitor of uPA, Factor Xa, and urokinase. Fluorophore allows direct monitoring of interactions of labeled enzyme. Does not inhibit tPA.
Biochem/physiol Actions
Cell permeable: no
Primary Target
UPA
UPA
Product does not compete with ATP.
Reversible: no
Target IC50: 100 nM for factor Xa
Preparation Note
Following initial thaw, aliquot and refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.
Reconstitute at 1 mg/ml in 10 mM HCl. Dilute with physiological buffers just prior to use.
Other Notes
Bajaj, S.P., et al. 1992. Proc. Natl. Acad. Sci. USA89, 152.
Bergmeyer, H.V. 1984. Methods Enzym. Anal. 5, 375.
Kettner, C., and Shaw, E. 1981. Methods Enzymol.80, 826.
Bergmeyer, H.V. 1984. Methods Enzym. Anal. 5, 375.
Kettner, C., and Shaw, E. 1981. Methods Enzymol.80, 826.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
保管分類
11 - Combustible Solids
WGK
WGK 1
引火点 (F)
Not applicable
引火点（°C）
Not applicable