252805
DHEA
≥97% (HPLC), powder, GABAA receptor negative modulator, Calbiochem®
別名:
DHEA, Dehydro- epi-androsterone, Dehydroisoandrosterone, Prasterone, 3-Hydroxyandrost-5-en-17-one
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この商品について
Assay:
≥97% (HPLC)
Form:
powder
Storage condition:
OK to freeze
製品名
DHEA, Major secretory steroidal product of the adrenal gland.
Quality Segment
description
Merck USA index - 14, 2871
assay
≥97% (HPLC)
form
powder
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
off-white
solubility
ethanol: 20 mg/mL
shipped in
ambient
storage temp.
10-30°C
SMILES string
O[C@H]1CC[C@@]2([C@@H]3[C@H]([C@H]4[C@](CC3)(C(=O)CC4)C)CC=C2C1)C
InChI
1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h3,13-16,20H,4-11H2,1-2H3/t13-,14-,15-,16-,18-,19-/m0/s1
InChI key
FMGSKLZLMKYGDP-USOAJAOKSA-N
General description
Major secretory steroidal product of the adrenal gland. DHEA and its sulfated metabolite, DHEA-S, are negative modulators of GABAA receptors.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Negative modulators of GABAA receptors
Negative modulators of GABAA receptors
Product does not compete with ATP.
Reversible: no
Other Notes
Hansen, S.L., et al. 1999. Mol. Pharmacol. 55, 489.
Imamura, M., and Prasad, C. 1998. Biochem. Biophys. Res. Commun.243, 771.
Majewska, M.D., et al. 1990. Brain Res.526, 143.
Imamura, M., and Prasad, C. 1998. Biochem. Biophys. Res. Commun.243, 771.
Majewska, M.D., et al. 1990. Brain Res.526, 143.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
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signalword
Warning
hcodes
Hazard Classifications
Repr. 2
保管分類
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable