324696
Methoxysuccinyl-Ala-Ala-Pro-Val-p-nitroanilide
A specific chromogenic substrate for human neutrophil elastase.
別名:
Elastase Substrate I, Colorimetric
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この商品について
実験式（ヒル表記法）:
C27H38N6O9
CAS番号:
分子量:
590.63
UNSPSC Code:
12352200
NACRES:
NA.54
MDL number:
Assay:
≥95% (HPLC)
Form:
lyophilized
Storage condition:
OK to freeze, desiccated
製品名
Elastase Substrate I, Colorimetric, A specific chromogenic substrate for human neutrophil elastase.
Quality Segment
assay
≥95% (HPLC)
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated
solubility
water: 1 mg/mL
shipped in
ambient
storage temp.
−20°C
SMILES string
[N+](=O)([O-])c1ccc(cc1)N[C@@H](C(C)C)C(=O)NC(=O)[C@H]2N(CCC2)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)CCC(=O)OC)C)C
InChI
1S/C27H38N6O9/c1-15(2)23(30-18-8-10-19(11-9-18)33(40)41)26(38)31-25(37)20-7-6-14-32(20)27(39)17(4)29-24(36)16(3)28-21(34)12-13-22(35)42-5/h8-11,15-17,20,23,30H,6-7,12-14H2,1-5H3,(H,28,34)(H,29,36)(H,31,37,38)/t16-,17-,20-,23-/m0/s1
InChI key
JWYKDZIEIWGSBN-OSAZLGQLSA-N
General description
A specific chromogenic substrate for human neutrophil elastase (Kcat/Km = 120,000 vs. 2700 for pancreatic elastase). Cleavage can be monitored at ~410 nm. Sold on the basis of substrate content.
Specific chromogenic substrate for human neutrophil elastase (kcat/Km = 120,000 versus pancreatic elastase: kcat/Km = 2,700). Cleavage can be monitored at 410 nm using ε = 8,800.
Biochem/physiol Actions
Cell permeable: no
Kcat/Km = 120,000 vs. 2700 for pancreatic elastase
Primary Target
Chromogenic substrate for human neutrophil elastase
Chromogenic substrate for human neutrophil elastase
Product does not compete with ATP.
Reversible: no
Physical form
Lyophilized from a solution containing 90 mg D-mannitol and 10 mg substrate.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Barrett, A.J., et al. 1989. Biochim. J.260, 259.
Nakajima, K., et al. 1979. J. Biol. Chem.254, 4027.
Nakajima, K., et al. 1979. J. Biol. Chem.254, 4027.
MeOSuc-Ala-Ala-Pro-Val-pNA
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
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保管分類
11 - Combustible Solids
一体何が起きているの？
WGK 3
引火点 (F)
Not applicable
引火点（°C）
Not applicable