344215
Formononetin
A phytoestrogenic isoflavone found in soy-based foods.
別名:
Formononetin, 7-Hydroxy-3-(4ʹ-methoxyphenyl)-4H-benzopyran-4-one
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この商品について
Assay:
≥90% (HPLC)
Form:
solid
Storage condition:
OK to freeze, protect from light
Quality Segment
description
Merck USA index - 14, 4244
assay
≥90% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
white to off-white
solubility
methanol: 2 mg/mL, DMSO: 200 mg/mL
shipped in
ambient
storage temp.
−20°C
SMILES string
O1c2c(ccc(c2)O)C(=O)C(=C1)c3ccc(cc3)OC
InChI
1S/C16H12O4/c1-19-12-5-2-10(3-6-12)14-9-20-15-8-11(17)4-7-13(15)16(14)18/h2-9,17H,1H3
InChI key
HKQYGTCOTHHOMP-UHFFFAOYSA-N
General description
A non-steroidal phytoestrogenic isoflavone found in soy-based food products. Has been shown to interact with human estrogen receptor with relatively low potency. Induces mammary gland proliferation in mice. Inhibits lecithin peroxidation induced by hydroxyl radicals. Also acts as a selective inhibitor of γ-isoform of alcohol dehydrogenase.
A phytoestrogenic isoflavone found in soy-based foods. Displays potent antioxidant properties and acts as a selective inhibitor of the γ-isoform of alcohol dehydrogenase. Shown to interact with human estrogen receptors with low potency. Induces mammary gland proliferation in mice.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Selective inhibitor of the γ-isoform of alcohol dehydrogenase
Selective inhibitor of the γ-isoform of alcohol dehydrogenase
Product does not compete with ATP.
Reversible: no
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Do not re-freeze any thawed aliquots.
Other Notes
Pool-Zobel, B.L., et al. 2000. Carcinogenesis 21, 1247.
Toda, S., and Shirataki, Y. 1999. Phytother. Res.13, 163.
Ruiz-Larrea, M.B., et al. 1997. Free Radic. Res.26, 63.
Keung, W.M. 1995. Biochem. Biophys. Res. Commun.215, 1137.
Wang, W., et al. 1995. Nutr. Cancer23, 131.
Miksicek, R.J. 1994. J. Steroid Biochem. Mol. Biol.49, 153.
Toda, S., and Shirataki, Y. 1999. Phytother. Res.13, 163.
Ruiz-Larrea, M.B., et al. 1997. Free Radic. Res.26, 63.
Keung, W.M. 1995. Biochem. Biophys. Res. Commun.215, 1137.
Wang, W., et al. 1995. Nutr. Cancer23, 131.
Miksicek, R.J. 1994. J. Steroid Biochem. Mol. Biol.49, 153.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Irritant (B)
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保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable