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Merck

3867

Hydrocortisone

≥98% (TLC), anti-inflammatory, solid

別名:

Hydrocortisone, Cortisol

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この商品について

実験式（ヒル表記法）:
C21H30O5
CAS番号:
50-23-7
分子量:
362.46
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD00011654

主要文書

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製品名

Hydrocortisone, Steroid hormone of the adrenal cortex with anti-inflammatory properties.

SMILES string

O[C@]1([C@@]2([C@H]([C@H]3[C@@H]([C@]4(CCC(=O)C=C4CC3)C)[C@H](C2)O)CC1)C)C(=O)CO

InChI

1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

InChI key

JYGXADMDTFJGBT-VWUMJDOOSA-N

description

RTECS - GM8925000
Merck USA index - 14, 4787

assay

≥98% (TLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white to off-white

solubility

ethanol: 15 mg/mL

shipped in

ambient

storage temp.

10-30°C

Quality Level

100

関連するカテゴリー

Biochem/physiol Actions

Cell permeable: no
Primary Target
Steroid hormone of the adrenal cortex with anti-inflammatory properties
Product does not compete with ATP.
Reversible: no

Disclaimer

Toxicity: Carcinogenic / Teratogenic (D)

General description

Steroid hormone of the adrenal cortex with anti-inflammatory properties.
Steroid synthesized by the adrenal cortex. Important in the regulation of protein, nucleic acid, and lipid metabolism. Pharmacologically, hydrocortisone is used to suppress the inflammatory response.

Preparation Note

Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 1 month at 4°C.
Heating to 37°C may be required for complete solubilization.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazard
GHS08

signalword

Danger

Hazard Classifications

Repr. 1A - STOT RE 2

target_organs

Adrenal gland,Bone marrow

保管分類

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

試験成績書（COA）

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以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Abhishek Mukherjee et al.
PLoS computational biology, 16(10), e1008300-e1008300 (2020-10-10)
Large nuclear deformations during migration through confined spaces have been associated with nuclear membrane rupture and DNA damage. However, the stresses associated with nuclear damage remain unclear. Here, using a quasi-static plane strain finite element model, we map evolution of
Lei Liu et al.
Journal of dairy science, 104(12), 12871-12880 (2021-09-07)
Susceptibility to mastitis is highest during the peripartal (transition) period and is often concomitant with other comorbidities such as ketosis. Although infection with pathogenic microorganisms and immune-dysfunction around calving clearly play key roles in mastitis development, other metabolic factors also
Xiaoxiang Hou et al.
Journal of neuroinflammation, 21(1), 148-148 (2024-06-06)
White matter injury (WMI) represents a significant etiological factor contributing to neurological impairment subsequent to Traumatic Brain Injury (TBI). CD36 receptors are recognized as pivotal participants in the pathogenesis of neurological disorders, including stroke and spinal cord injury. Furthermore, dynamic
Hong-Yu Wu et al.
iScience, 27(6), 109850-109850 (2024-05-23)
Milk fat is an important indicator for evaluating the quality of cow's milk. In this study, we used bovine mammary epithelial cells (BMECs) to investigate the role and molecular mechanism of KLF4 in the regulation of milk fat synthesis. The
Simone Sandoval et al.
Frontiers in immunology, 14, 1193535-1193535 (2023-11-30)
Neuropilin-1 (Nrp1), a transmembrane protein expressed on CD4+ T cells, is mostly studied in the context of regulatory T cell (Treg) function. More recently, there is increasing evidence that Nrp1 is also highly expressed on activated effector T cells and
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関連コンテンツ

グローバルトレードアイテム番号

カタログ番号GTIN
3867-1GMCN07790788049782

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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