437620
Lipopolysaccharide
from E. coli J5 mutant, Nitric oxide synthase stimulator, lyophilized
別名:
Lipopolysaccharide, E. coli J5
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この商品について
Form:
lyophilized
Storage condition:
OK to freeze
製品名
Lipopolysaccharide, E. coli J5, Mutant of E. coli O111: B4. Stimulates the activity of inducible nitric oxide synthase. Induces apoptosis in mouse thymus and swine lymphocytes.
Quality Segment
description
RTECS - OJ0895400
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
impurities
<2.5% Protein, 5.0-10.0% 2-keto-3-deoxyoctonate (KDO)
solubility
water: 1 mg/mL
anion traces
phosphate (PO43-): 6.0-15.0%
shipped in
ambient
storage temp.
2-8°C
General description
Mutant of E. coli 0111:B4. Stimulates the activity of inducible nitric oxide synthase. Induces apoptosis in mouse thymus and swine lymphocytes. Highly purified preparation.
Mutant of E. coli O111: B4. Stimulates the activity of inducible nitric oxide synthase. Induces apoptosis in mouse thymus and swine lymphocytes.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Inducible nitric oxide synthase
Inducible nitric oxide synthase
Product does not compete with ATP.
Reversible: no
Preparation Note
Following reconstitution refrigerate (4°C). Stock solutions are stable for up to 1 year at 4°C.
LPS will form a suspension in H₂O; slight warming and vortexing may be required to achieve complete dispersion in H₂O. Addition of 0.5% triethylamine will also help with dispersion; triethylamine is very basic and can be neutralized with Trix-HCl to avoid hydrolysis of the fatty acid chains.
Other Notes
Hattori, S., et al. 1995. Biochem. Mol. Biol. Int.35, 177.
Mayeux, P.R., et al. 1995. Biochem. Pharmacol.49, 115.
Norimatsu, M., et al. 1995. Infect. Immun.63, 1122.
Feinstein, D.L., et al. 1993. J. Neurochem.60, 1945.
Zhang, Y.H., et al. 1993. Infect. Immun.61, 5044.
Mayeux, P.R., et al. 1995. Biochem. Pharmacol.49, 115.
Norimatsu, M., et al. 1995. Infect. Immun.63, 1122.
Feinstein, D.L., et al. 1993. J. Neurochem.60, 1945.
Zhang, Y.H., et al. 1993. Infect. Immun.61, 5044.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Harmful (C)
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral
保管分類
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
437620-MG: + 437620-5MG:
jan