444225
MMP-3 Inhibitor II
The MMP-3 Inhibitor II, also referenced under CAS 161314-17-6, controls the biological activity of MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
別名:
MMP-3 Inhibitor II, N-Isobutyl-N-(4-methoxyphenylsulfonyl)-glycylhydroxamic Acid, NNGH
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この商品について
実験式（ヒル表記法）:
C13H20N2O5S
CAS番号:
分子量:
316.37
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (TLC)
Form:
solid
Storage condition:
OK to freeze
Quality Segment
assay
≥98% (TLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white
solubility
DMSO: 30 mg/mL, ethanol: 8 mg/mL
shipped in
ambient
storage temp.
10-30°C
SMILES string
[S](=O)(=O)(N(CC(C)C)CC(=O)NO)c1ccc(cc1)OC
InChI
1S/C13H20N2O5S/c1-10(2)8-15(9-13(16)14-17)21(18,19)12-6-4-11(20-3)5-7-12/h4-7,10,17H,8-9H2,1-3H3,(H,14,16)
InChI key
JIRXORZYIXSWOB-UHFFFAOYSA-N
General description
A cell-permeable, potent inhibitor of human MMP-3 (stromelysin; Ki = 130 nM).
A potent and cell-permeable inhibitor of human MMP-3 (Ki = 130 nM).
Biochem/physiol Actions
Cell permeable: yes
Primary Target
human MMP-3
human MMP-3
Product does not compete with ATP.
Reversible: no
Target Ki: 130 nM against human MMP-3
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Other Notes
Kato, N., et al. 2002. Genome Informatics13, 272.
MacPherson, L.J., et al. 1997. J. Med. Chem. 40, 2525.
MacPherson, L.J., et al. 1997. J. Med. Chem. 40, 2525.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable