5.05227
(-)-Cytisine
別名:
(-)-Cytisine, nAChR Agonist, (-)-Cytisine, Nicotinic Acetylcholine Receptor Agonist, (-)-Cytisine, Baptitoxine, Sophorine
ログインで組織・契約価格をご覧ください。
サイズを選択してください
表示を変更する
この商品について
Assay:
≥99% (HPLC)
Form:
solid
Storage condition:
OK to freeze, protect from light
assay
≥99% (HPLC)
Quality Segment
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
pale yellow
solubility
water: 100 mM
storage temp.
2-8°C
SMILES string
N21C[C@@H]3CNC[C@H](C3)C2=CC=CC1=O
InChI
1S/C11H14N2O/c14-11-3-1-2-10-9-4-8(5-12-6-9)7-13(10)11/h1-3,8-9,12H,4-7H2/t8-,9-/m0/s1
InChI key
ANJTVLIZGCUXLD-IUCAKERBSA-N
General description
A potent agonist selective for neuronal nAChRs (Ki = 2, 5890, 480, 329, and 492 nM at α4β2, α7, α3β4, α6/α4β4, α1β1γδ, respectively). Clinically used as a smoking cessation medicine and often used in addiction studies.
Biochem/physiol Actions
Primary Target
nAChR
nAChR
Reversible: yes
Target Ki: 2, 5890, 480, 329, and 492 nM at &alpha
Preparation Note
Following reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Chen, Y., et al., 2012. Br J Pharmacol.165, 1006.
West, R., 2011, N. Engl. J. Med.365, 1193.
Happe, K., et al., 1994. Neurosci.62, 929.
Reavill, C. et al., 1990. Neuropharmacol.29, 619.
West, R., 2011, N. Engl. J. Med.365, 1193.
Happe, K., et al., 1994. Neurosci.62, 929.
Reavill, C. et al., 1990. Neuropharmacol.29, 619.
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Toxic (F)
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
保管分類
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
5052270001: + 5052270002:
jan