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この商品について
NACRES:
NA.77
UNSPSC Code:
12352200
Form:
solid
Storage condition:
OK to freeze, protect from light
Quality Segment
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
shipped in
ambient
storage temp.
−20°C
General description
Contains 5 mg of ALLN (Cat. No. 208719), 100 μg each of Epoxomicin (Cat. No. 324800), and clasto-Lactacystin β-Lactone (Cat. No. 426102). Supplied with a data sheet.
Proteasomes are large multi-subunit protease complexes, which selectively degrade intracellular proteins. A protein marked for degradation is attached to multiple molecules of ubiquitin, a 76-amino acid protein, which escorts it for rapid hydrolysis, by the 26S proteasome. The proteolytic core of this complex consists of the 20S proteasome, which contains multiple peptidase activities and has a molecular mass of ~700 kDa. Recently several potent, cell-permeable proteasome inhibitors have been developed.
The Calbiochem brand offers a set that includes 3 proteasome inhibitors with varying inhibtory effects.
The table below outlines some of the physical and biological properties of these compounds.
The Calbiochem brand offers a set that includes 3 proteasome inhibitors with varying inhibtory effects.
The table below outlines some of the physical and biological properties of these compounds.
Biochem/physiol Actions
Primary Target
calpain 1, calpain 2
calpain 1, calpain 2
Secondary Target
cathepsin B, cathepsin L
cathepsin B, cathepsin L
Packaging
Packaged under inert gas
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
保管分類
11 - Combustible Solids
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
539165-1SET:
jan
試験成績書(COA)
製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。