539165
Proteasome Inhibitor Set II
The Proteasome Inhibitor Set II controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
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この商品について
NACRES:
NA.77
UNSPSC Code:
12352200
Form:
solid
Storage condition:
OK to freeze, protect from light
Quality Segment
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
shipped in
ambient
storage temp.
−20°C
General description
Contains 5 mg of ALLN (Cat. No. 208719), 100 μg each of Epoxomicin (Cat. No. 324800), and clasto-Lactacystin β-Lactone (Cat. No. 426102). Supplied with a data sheet.
Proteasomes are large multi-subunit protease complexes, which selectively degrade intracellular proteins. A protein marked for degradation is attached to multiple molecules of ubiquitin, a 76-amino acid protein, which escorts it for rapid hydrolysis, by the 26S proteasome. The proteolytic core of this complex consists of the 20S proteasome, which contains multiple peptidase activities and has a molecular mass of ~700 kDa. Recently several potent, cell-permeable proteasome inhibitors have been developed.
The Calbiochem
The table below outlines some of the physical and biological properties of these compounds.
The Calbiochem
The table below outlines some of the physical and biological properties of these compounds.
Biochem/physiol Actions
Primary Target
calpain 1, calpain 2
calpain 1, calpain 2
Secondary Target
cathepsin B, cathepsin L
cathepsin B, cathepsin L
Packaging
Packaged under inert gas
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
保管分類
11 - Combustible Solids