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662041

U-73343

Name: U-73343
Brand: MM

A cell-permeable analog of U-73122 that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.

別名:

U-73343, 1-[6-((17β-3-Methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl]-2,5-pyrrolidinedione

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この商品について

実験式（ヒル表記法）:

C₂₉H₄₂N₂O₃

CAS番号:

142878-12-4

分子量:

466.66

UNSPSC Code:

51111800

NACRES:

NA.77

MDL number:

MFCD00211221

Assay:

≥98% (HPLC)

Form:

solid

Storage condition:

OK to freeze

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特性

Quality Segment

100

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze

color

off-white

solubility

ethanol: 1 mg/mL, DMSO: 2 mg/mL, chloroform: 200 mg/mL

shipped in

ambient

storage temp.

10-30°C

SMILES string

N5(C(=O)CCC5=O)CCCCCCN[C@@H]1[C@@]2([C@H]([C@H]3[C@H](CC2)c4c(cc(cc4)OC)CC3)CC1)C

InChI

1S/C29H42N2O3/c1-29-16-15-23-22-10-8-21(34-2)19-20(22)7-9-24(23)25(29)11-12-26(29)30-17-5-3-4-6-18-31-27(32)13-14-28(31)33/h8,10,19,23-26,30H,3-7,9,11-18H2,1-2H3/t23-,24-,25+,26+,29+/m1/s1

InChI key

CJHWFIUASFBCKN-ZRJUGLEFSA-N

詳細

General description

A cell-permeable analog of U-73122 (Cat. No. 662035) that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.

Biochem/physiol Actions

Cell permeable: yes

Primary Target
Negative control of U-73122 in the inhibition of phospholipase C

Product does not compete with ATP.

Reversible: no

Preparation Note

For storage in chloroform, aliquot into single use volumes, evaporate to dryness under a stream of nitrogen and freeze (-20°C). DMSO stocks solutions are stable for up to 6 months at -20°C.

Other Notes

Tatrai, A., et al. 1994. Biochim. Biophys. Acta 1224, 595.
Bleasdale, J.E., et al. 1990. J. Pharmacol. Exp. Ther.255, 756.
Smith, R.J., et al. 1990. J. Pharmacol. Exp. Ther.253, 688.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Irritant (B)

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保管分類

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c