8.18203
(9-Fluorenylmethyl) chloroformate
for synthesis
別名:
(9-Fluorenylmethyl) chloroformate, Chloroformic acid 9-fluorenylmethyl ester, FMOCCl
ログインで組織・契約価格をご覧ください。
サイズを選択してください
表示を変更する
この商品について
実験式（ヒル表記法）:
C15H11ClO2
CAS番号:
分子量:
258.70
UNSPSC Code:
12352108
EC Index Number:
249-313-6
NACRES:
NA.22
MDL number:
Grade:
synthesis grade
grade
synthesis grade
Quality Segment
form
powder
dilution
(for synthesis)
mp
60-63 °C
application(s)
peptide synthesis
storage temp.
15-25°C
SMILES string
ClC(=O)OCC1c2c(cccc2)c3c1cccc3
InChI
1S/C15H11ClO2/c16-15(17)18-9-14-12-7-3-1-5-10(12)11-6-2-4-8-13(11)14/h1-8,14H,9H2
InChI key
IRXSLJNXXZKURP-UHFFFAOYSA-N
General description
(9-Fluorenylmethyl) chloroformate, also known as Fmoc chloride, is a highly versatile reagent with varied applications in organic synthesis. It is most frequently used to introduce the base-labile Fmoc-protecting group to amine functionalities, particularly during the production of Fmoc-protected amino acids. Fmoc-chloride has also been used to generate mixed carboxylic and carbonic anhydrides to facilitate amide and ester bond formation. It is soluble in common organic solvents such as dichloromethane, tetrahydrofuran, and dimethylformamide.
Application
Recent applications of (9-Fluorenylmethyl) chloroformate include:
- (9-Fluorenylmethyl) chloroformate can be used as a coupling reagent.
- In the synthesis of amino acid esters. Fmoc chloride activates the carboxylic acid group of the amino acid, allowing it to react with an alcohol to form the ester.
- In the preparation of lysogangliosides.
- In the solid-phase peptide synthesis of DOPA-containing peptides.
Still not finding the right product?
Explore all of our products under (9-Fluorenylmethyl) chloroformate
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
supp_hazards
flash_point_f
Not applicable
flash_point_c
Not applicable
保管分類
8A - Combustible corrosive hazardous materials