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Merck

HADK2MAG-61K

MILLIPLEX® Human Adipokine Panel

Configurable Human Adipokine 8-Plex Panel 2

別名:

adipocyte inflammation marker listing, adipokine assay snapshot, adipokine biomarker profile, adipose tissue cytokine panel, human adipokine assay overview, human adipokine panel summary, human cytokine product info, human metabolic research tool, inflammation and metabolism biomarker kit, multiplex adipokine product sheet

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この商品について

UNSPSC Code:
12161503
NACRES:
NA.47
eCl@ss:
32161000

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製品名

MILLIPLEX® Human Adipokine Panel,

species reactivity

human

Quality Level

200

description

Configurable Human Adipokine 8-Plex Panel 2

assay range

accuracy: 87%
(IL-8), accuracy: 91%
(TNFα), accuracy: 94%
(Insulin), standard curve range: 0.64-10,000 pg/mL
(IL-8), standard curve range: 0.64-10,000 pg/mL
(NGF), standard curve range: 0.64-10,000 pg/mL
(TNF-α), standard curve range: 0.96-15,000 pg/mL
(IL-6), standard curve range: 1.3-20,000 pg/mL
(IL-1β), standard curve range: 1.3-20,000 pg/mL
(MCP-1), standard curve range: 38-600,000 pg/mL
(Leptin), standard curve range: 9.6-150,000 pg/mL
(HGF), standard curve range: 9.6-150,000 pg/mL
(Insulin), inter-assay cv: <15%
intra-assay cv: <10%
(IL-1β), inter-assay cv: <15%
intra-assay cv: <10%
(IL-6), inter-assay cv: <15%
intra-assay cv: <10%
(IL-8), inter-assay cv: <15%
intra-assay cv: <10%
(Insulin), inter-assay cv: <15%
intra-assay cv: <10%
(Leptin), inter-assay cv: <15%
intra-assay cv: <10%
(MCP-1), inter-assay cv: <15%
intra-assay cv: <10%
(NGF), inter-assay cv: <20%
intra-assay cv: <10%
(TNFα)

technique(s)

multiplexing: suitable

input

serum plasma

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

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General description

Adipokines are signaling proteins secreted by adipose tissue that influence inflammation, metabolism, and energy balance. This set of biomarkers—IL-1β, IL-6, IL-8/CXCL8, Insulin, Leptin, MCP-1/CCL2, NGF, and TNFα—captures the interplay between metabolic regulation and immune response. These analytes are associated with insulin sensitivity, appetite control, inflammatory signaling, and neuroimmune interactions, making them highly relevant for research in obesity, type 2 diabetes, cardiovascular disease, and chronic inflammation.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 8 analytes in human serum or plasma samples.

Analytes included: IL-1β, IL-6, IL-8/CXCL8, Insulin, Leptin, MCP-1/CCL2, NGF, TNFα

Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

Features:
  • Targets key adipokines and cytokines involved in metabolic and inflammatory pathways
  • Includes 8 analytes relevant to insulin signaling, immune response, and adipose tissue function
  • Multiplex format enables simultaneous detection from minimal sample volume
  • Compatible with human serum and plasma samples
  • Designed for research in obesity, insulin resistance, inflammation, and metabolic syndrome
Benefits:
  • Provides a comprehensive profile of inflammatory and metabolic biomarkers
  • Supports investigation of adipose tissue dysfunction and systemic inflammation
  • Facilitates evaluation of therapeutic interventions in metabolic and endocrine disorders
  • Enables high-throughput analysis with reduced sample and reagent use
  • Delivers reproducible, sensitive results for translational and clinical research

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

保管分類

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Please refer to KIT Component information

pdsc

Please refer to KIT Component information

prtr

Please refer to KIT Component information

fsl

Please refer to KIT Component information

ishl_indicated

Please refer to KIT Component information

ishl_notified

Please refer to KIT Component information

cart

キットコンポーネントの情報を参照してください

jan

試験成績書（COA）

製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Racial differences in HbA1c: a cross-sectional analysis of a Brazilian public primary care population.
de Miranda, VA; Cruz Filho, RA; de Oliveira, TS; Moscavitch, SD; Kang, HC; Miranda Chagas et al.
Primary Care Diabetes null
Hwallip Bae et al.
Neuropsychiatric disease and treatment, 10, 2153-2157 (2014-11-25)
The role of neurotrophic factors has been highlighted as a cause of decline in the cognitive function of alcohol-dependent patients. It is known that nerve-growth factor (NGF), one of the neurotrophins, is related to the growth and differentiation of nerve
Maria A Ramos-Roman et al.
Diabetes, 69(8), 1624-1635 (2020-05-10)
Milk production may involve a transient development of insulin resistance in nonmammary tissues to support redistribution of maternal macronutrients to match the requirements of the lactating mammary gland. In the current study, adipose and liver metabolic responses were measured in
Altered promoter methylation of PDK4, IL1 B, IL6, and TNF after Roux-en Y gastric bypass.
Kirchner, H; Nylen, C; Laber, S; Barres, R; Yan, J; Krook, A; Zierath, JR; Naslund, E
Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery null
Annalisa Berzigotti et al.
Hepatology (Baltimore, Md.), 65(4), 1293-1305 (2016-12-21)
Obesity increases the risk of clinical decompensation in cirrhosis, possibly by increasing portal pressure. Whether weight reduction can be safely achieved through lifestyle (LS) changes (diet and exercise) in overweight/obese patients with cirrhosis, and if weight loss reduces portal pressure
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関連コンテンツ

Multiplexing Metabolic Syndrome Biomarkers | MILLIPLEX® Assays

Multiplex immunoassays, such as MILLIPLEX® multiplex metabolic assays, are critical in metabolic syndrome research because they provide a full picture of the different conditions related to it, like diabetes and obesity, as well as save time and sample volume.

メタボリックシンドロームバイオマーカーのマルチプレックス | MILLIPLEX® アッセイ

MILLIPLEX®マルチプレックス代謝アッセイなどのマルチプレックス・イムノアッセイは、メタボリックシンドローム研究に重要です。糖尿病や肥満など、関連するさまざまな病態の全体像を把握でき、時間とサンプル量を節約できるためです。

The Power of Biomarker Analysis
Protocol- HADK2MAG-61K
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