IF014
Interferon-β Protein, Recombinant human
Recombinant Human Interferon Beta 1a (Hu-IFNbeta 1a).
別名:
Fibroblast Interferon
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この商品について
UNSPSC Code:
12352202
NACRES:
NA.77
eCl@ss:
32160405
Form:
liquid
Assay:
≥95% (one N-glycosylation site)
Biological source:
human
Recombinant:
expressed in CHO cells
製品名
Interferon-β Protein, Recombinant human, Recombinant Human Interferon Beta 1a (Hu-IFNbeta 1a).
biological source
human
recombinant
expressed in CHO cells
assay
≥95% (one N-glycosylation site)
form
liquid
specific activity
3.99 x 108 U/mg
manufacturer/tradename
Chemicon®
concentration
1 x 106 units/mL
technique(s)
cell culture | mammalian: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
Quality Level
Analysis Note
Specific Activity: Determined by assaying inhibition of virus-induced cytopathic effect.In this antiviral assay for interferon, about 1 unit/ml of interferon is the quantity necessary to produce a cytopathic effect of 50%.The units are determined with respect to the international reference standard for human interferon beta (Hu-IFNbeta) provided by the National Institutes of Health.Unit of activity measured on VERO cells with vesicular stomatitis virus (VSV).
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Product Source: cDNA obtained from human fibroblast mRNA expressed in CHO cells.
Recombinant Human Interferon Beta 1a (Hu-IFNbeta 1a). Molecular weight is ~23 kDa.
Other Notes
Replaces: IF008
Physical form
Frozen liquid in 50 mM NaOAc, pH 5.5, containing 0.1% BSA.
Preparation Note
After receipt, this product should be kept at -70°C or below for retention of full activity.
Thaw product vial by incubation cold tap water until just thawed. Thawed IFNβ should be
stored in working aliquots at -70°C for up to six months. Avoid multiple freeze/thaw cycles.
Refreezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of the
product should be in buffers containing protein such as 0.1% bovine serum albumin (BSA).
Thaw product vial by incubation cold tap water until just thawed. Thawed IFNβ should be
stored in working aliquots at -70°C for up to six months. Avoid multiple freeze/thaw cycles.
Refreezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of the
product should be in buffers containing protein such as 0.1% bovine serum albumin (BSA).
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
保管分類
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
IF014:
jan
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Colton R Martens et al.
PLoS pathogens, 18(2), e1010342-e1010342 (2022-02-23)
Viral infection of the heart is a common but underappreciated cause of heart failure. Viruses can cause direct cardiac damage by lysing infected cardiomyocytes. Inflammatory immune responses that limit viral replication can also indirectly cause damage during infection, making regulatory
Fanning Zeng et al.
Cells, 9(12) (2020-12-10)
Genetic knock-in using homology-directed repair is an inefficient process, requiring the selection of few modified cells and hindering its application to primary cells. Here, we describe Homology independent gene Tagging (HiTag), a method to tag a protein of interest by
Zhaowei Chu et al.
Nature communications, 13(1), 1859-1859 (2022-04-08)
The cohesin complex participates in the organization of 3D genome through generating and maintaining DNA loops. Stromal antigen 2 (STAG2), a core subunit of the cohesin complex, is frequently mutated in various cancers. However, the impact of STAG2 inactivation on
Daniel Vogt et al.
Virology, 540, 150-159 (2020-01-14)
During DNA virus infections, detection of cytosolic DNA by the cGAS-STING pathway leads to activation of IFN-β. Kaposi's Sarcoma Herpesvirus (KSHV), an oncogenic DNA virus, is the etiological agent of Kaposi's Sarcoma, an endothelial cell (EC)-based tumor. To investigate the
Sarah Aref et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 28(4), 1043-1055 (2020-02-23)
The mechanism of tumor-selective replication of oncolytic measles virus (MV) is poorly understood. Using a stepwise model of cellular transformation, in which oncogenic hits were additively expressed in human bone marrow-derived mesenchymal stromal cells, we show that MV-induced oncolysis increased
関連コンテンツ
グローバルトレードアイテム番号
| カタログ番号 | GTIN |
|---|---|
| IF014 | 04053252470646 |
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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