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Merck

MT17MAG47PMX25BK

MILLIPLEX® Mouse TH17 Panel

Bulk (Space Saver) Premixed Mouse Th17 25-Plex Panel

別名:

Mouse TH17 Panel, TH17 Magnetic Bead Panel, murine Th17 assay

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この商品について

UNSPSC Code:
12161503
NACRES:
NA.47
eCl@ss:
32161000
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製品名

MILLIPLEX® Mouse TH17 Panel,

species reactivity

human

Quality Segment

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

assay range

linearity: 111.0%
(1:04), linearity: 113.1%
(1:08), standard curve range: 1.5-1,500 pg/mL
(IL-4), standard curve range: 10-10,000 pg/mL
(IL-17F), standard curve range: 127-130,000 pg/mL
(IL-28B), standard curve range: 15-15,000 pg/mL
(IL-1β), standard curve range: 2.4-2,500 pg/mL
(IL-22), standard curve range: 20-20,000 pg/mL
(IL-10, IL-12(p70), & IL-21), standard curve range: 3.4-3,500 pg/mL
(TNFα), standard curve range: 34-35,000 pg/mL
(GM-CSF & IL-15), standard curve range: 342-350,000 pg/mL
(IL-23), standard curve range: 39-40,000 pg/mL
(IL-13 & IL-17A), standard curve range: 4.9-5,000 pg/mL
(IL-5), standard curve range: 488-500,000 pg/mL
(TNFβ), standard curve range: 49-50,000 pg/mL
(CD40L IL-31 & MIP-3α), standard curve range: 586-600,000 pg/mL
(IL-17E/ IL-25), standard curve range: 6.9-6,000 pg/mL
(IL-2), standard curve range: 7.8-8,000 pg/mL
(IFNγ & IL-6), standard curve range: 78-80,000 pg/mL
(IL-33), standard curve range: 879-900,000 pg/mL
(IL-27)

technique(s)

multiplexing: suitable

input

cell culture supernatant(s)
plasma
serum

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

Th17 cells, a subset of CD4+ T helper cells, play a crucial role in immune responses by producing a range of cytokines, particularly interleukin-17 (IL-17). In mice, Th17 cytokines, including IL-17A, IL-17F, and IL-22, are involved in promoting inflammation and are key players in the defense against extracellular pathogens, as well as in the pathogenesis of autoimmune diseases. These cytokines help to recruit neutrophils and enhance the production of antimicrobial peptides, contributing to the host′s immune response.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 25 analytes in mouse serum, plasma, and cell culture supernatants.

Analytes included: CD40 Ligand, GM-CSF, IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12 (p70), IL-13, IL-15, IL-17A, IL-17E/IL-25, IL-17F, IL-21, IL-22, IL-23, IL-27, IL-28B, IL-31, IL-33, MIP-3α/CCL20, TNF-α, TNFβ

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

  • Th17 Pathway Insights in One Assay: Unlock a complete view of Th17-related immune activity with simultaneous measurement of key cytokines—perfect for uncovering disease mechanisms.
  • Efficient Use of Precious Samples: Requires only a small volume, preserving valuable mouse specimens while delivering robust data.
  • Boost Productivity with Multiplex Power: Analyze multiple biomarkers at once using Luminex® magnetic bead technology—saving time, reducing costs, and increasing throughput.
  • Built for Mouse Research: Specifically formulated for mouse-based studies, ensuring compatibility and consistent results across sample types.
  • Advance Autoimmune and Cancer Research: Ideal for exploring Th17 involvement in chronic inflammation, immune dysregulation, and tumor progression.

Legal Information

Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.


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Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

保管分類

10 - Combustible liquids

wgk

WGK 3


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

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prtr

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fsl

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ishl_indicated

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ishl_notified

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