480001
NDSB-195
A non-detergent sulfobetaine. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins.
別名:
NDSB-195, Dimethylethylammonium Propane Sulfonate
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この商品について
実験式（ヒル表記法）:
C7H17NO3S
CAS番号:
分子量:
195.28
MDL number:
NACRES:
NA.21
UNSPSC Code:
12352200
製品名
NDSB-195, A non-detergent sulfobetaine. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins.
InChI key
NNCRHRDBFDCWPA-UHFFFAOYSA-N
SMILES string
[S](=O)(=O)([O-])CCC[N+](CC)(C)C
assay
≥95% (TLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated (hygroscopic)
color
white
solubility
water: soluble
shipped in
ambient
storage temp.
15-25°C
Quality Level
Application
- Protein stabilizer, NDSB-195, enhances the dynamics of the β4 -α2 loop of ubiquitin.: This research explores how NDSB-195 stabilizes proteins by enhancing the dynamics of the β4-α2 loop of ubiquitin, providing insights into its mechanism of action as a protein stabilizer (Wang et al., 2016).
- Suppression of problematic compound oligomerization by cosolubilization of nondetergent sulfobetaines.: The study demonstrates the effectiveness of NDSB-195 in suppressing the oligomerization of problematic compounds, showcasing its utility in biochemical and pharmaceutical applications (Mizukoshi et al., 2015).
- Interaction of anti-aggregation agent dimethylethylammonium propane sulfonate with acidic fibroblast growth factor.: This article discusses the interaction of NDSB-195 with acidic fibroblast growth factor, emphasizing its role in preventing protein aggregation during biochemical processes (Xiang et al., 2008).
- Preparation, crystallization and preliminary X-ray diffraction analysis of the DNA-binding domain of the Ets transcription factor in complex with target DNA.: The study uses NDSB-195 in the preparation and crystallization process, enhancing the stability and quality of the DNA-binding domain crystals for X-ray diffraction analysis (Suwa et al., 2008).
Disclaimer
Toxicity: Irritant (B)
General description
A non-detergent sulfobetaine. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. Zwitterionic over a wide pH range. Does not absorb significantly in the near-UV range. Easily removed by dialysis.
Other Notes
Goldberg, M.E., et al. 1996. Folding & Design 1, 21.
Vuillard, L., et al. 1995. Anal. Biochem. 230, 290.
Vuillard, L., et al. 1995. Biochem. J. 305, 337.
Vuillard, L., et al. 1994. FEBS Lett.353, 294.
Vuillard, L., et al. 1995. Anal. Biochem. 230, 290.
Vuillard, L., et al. 1995. Biochem. J. 305, 337.
Vuillard, L., et al. 1994. FEBS Lett.353, 294.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
保管分類
11 - Combustible Solids
wgk
WGK 3
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
グローバルトレードアイテム番号
| カタログ番号 | GTIN |
|---|---|
| 480001-25GMCN | 04055977201758 |
| 480001-5GMCN | 04055977201765 |
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