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Merck

CBL1337F

Anti-PECAM-1 Antibody, clone 390, FITC conjugated

clone 390, Chemicon®, from rat

別名:

CD31

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この商品について

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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製品名

Anti-PECAM-1 Antibody, clone 390, FITC conjugated, clone 390, Chemicon®, from rat

biological source

rat

conjugate

FITC conjugate

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

390, monoclonal

species reactivity

mouse

manufacturer/tradename

Chemicon®

technique(s)

flow cytometry: suitable
immunohistochemistry: suitable

isotype

IgG2aκ

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... PECAM1(5175)

関連するカテゴリー

Application

Flow Cytometry: = 1 μg per 10e6 cells in 100 μL volume

Immunohistochemistry: acteone fixed frozen tissue sections.

Optimal working dilutions must be determined by the end user.
Research Category
Cell Structure
Research Sub Category
Adhesion (CAMs)
This Anti-PECAM-1 Antibody, clone 390, FITC conjugated is validated for use in FC, IH for the detection of PECAM-1.

Biochem/physiol Actions

CBL1337 recognizes mouse PECAM-1, a 130-140 kDa type 1 integral membrane glycoprotein. This antibody has been shown to inhibit the aggregation of L cells transfected with a variant form of PECAM-1 (DeLisser, 1993).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

PECAM-1 is a type I integral membrane glycoprotein, and a member of the immunoglobulin superfamily of cell surface receptors. PECAM-1 is constitutively expressed on the surface of endothelial cells where it is concentrated at cell junctions. PECAM-1 is also expressed at low levels on all leukocytes and platelets. Homotypic interaction of CD31 is important in cell-cell interaction, cell-matrix interaction and signal transduction.

Immunogen

Mouse leukocyte cell line 32D

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Purified immunoglobulin conjugated to fluorescein. Liquid in in phosphate buffered saline containing 0.1% sodium azide.

Preparation Note

Maintain at 2°-8°C for up to 12 months from date of receipt. DO NOT FREEZE.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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保管分類

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


試験成績書(COA)

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文書ライブラリにアクセスする

Sofia Urner et al.
The EMBO journal, 38(2) (2018-12-07)
Vascular endothelial growth factor receptor-3 (VEGFR3) signalling promotes lymphangiogenesis. While there are many reported mechanisms of VEGFR3 activation, there is little understanding of how VEGFR3 signalling is attenuated to prevent lymphatic vascular overgrowth and ensure proper lymph vessel development. Here
Lara Planas-Paz et al.
The EMBO journal, 31(4), 788-804 (2011-12-14)
In the mammalian embryo, few mechanical signals have been identified to influence organ development and function. Here, we report that an increase in the volume of interstitial or extracellular fluid mechanically induces growth of an organ system, that is, the

グローバルトレードアイテム番号

カタログ番号GTIN
CBL1337F04053252278334

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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