FCMAB110P
Anti-phospho-ATM (Ser1981) Antibody, clone 10H11.E12 PE conjugate
clone 10H11.E12, from mouse, PE
別名:
A-T, mutated
AT mutated
TEL1, telomere maintenance 1, homolog
ataxia telangiectasia mutated
ataxia telangiectasia mutated (includes complementation groups A, C and D)
ataxia telangiectasia mutated protein
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この商品について
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
PE
Clone:
10H11.E12, monoclonal
Application:
flow cytometry
Species reactivity:
rat, mouse, human
Citations:
3
Technique(s):
flow cytometry: suitable
Uniprot accession no.:
製品名
Anti-phospho-ATM (Ser1981) Antibody, clone 10H11.E12 PE conjugate, clone 10H11.E12, from mouse, PE
biological source
mouse
conjugate
PE
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
10H11.E12, monoclonal
species reactivity
rat, mouse, human
technique(s)
flow cytometry: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
phosphorylation (pSer1981)
Quality Level
Gene Information
human ... ATM(472)
Physical form
Purified mouse monoclonal IgG1κ conjugated to phycoerythrin in PBS with less than 0.09% sodium azide and 15 mg/mL BSA.
Immunogen
KLH-conjugated, synthetic peptide corresponding to human ATM phosphorylated at Ser1981.
Epitope: Phosphorylated at and around Ser1981
Analysis Note
Control
Irradiated HeLa cells
Irradiated HeLa cells
Evaluated by Flow Cytometry with HeLa cells.
Application
Anti-phospho-ATM (Ser1981) Antibody, clone 10H11.E12 PE conjugate detects level of phospho-ATM (Ser1981) & has been published & validated for use in FC.
Biochem/physiol Actions
Antibody recognizes ATM phosphorylated at Ser1981.
Predicted to cross-react with rat based on sequence homology
General description
N-terminal c-Myc, GST-tagged, recombinant human Cardiac Troponin I full length, expressed by baculovirus in Sf21 insect cells. Purified using glutathione sepharose.
~370 kDa Calculated
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保管分類
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Yiting Lim et al.
International journal of radiation oncology, biology, physics, 84(3), 800-806 (2012-03-27)
We have previously shown that the antimalarial agent chloroquine can abrogate the lethal cellular effects of low-dose-rate (LDR) radiation in vitro, most likely by activating the ataxia-telangiectasia mutated (ATM) protein. Here, we demonstrate that chloroquine treatment also protects against lethal doses
S Masneri et al.
Stem cell research, 41, 101596-101596 (2019-11-02)
Using a Sendai Virus based vector delivering Yamanaka Factors, we generated induced Pluripotent Stem Cells (iPSCs) from peripheral blood mononuclear cells of a patient affected by Ataxia Telangiectasia (AT), caused by a novel homozygous deletion in ATM, spanning exons 5-7.
Sabrina Fritah et al.
Cancers, 12(9) (2020-09-16)
Resistance to chemotherapy by temozolomide (TMZ) is a major cause of glioblastoma (GBM) recurrence. So far, attempts to characterize factors that contribute to TMZ sensitivity have largely focused on protein-coding genes, and failed to provide effective therapeutic targets. Long noncoding
グローバルトレードアイテム番号
| カタログ番号 | GTIN |
|---|---|
| FCMAB110P | 04053252405143 |
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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