27029
コール酸ナトリウム 水和物
≥97.0% (dried material, NT)
別名:
3α,7α,12α-トリヒドロキシ-5β-コラン-24-酸 ナトリウム塩, コール酸 ナトリウム塩
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この商品について
description
anionic
Quality Segment
assay
≥97.0% (dried material, NT)
form
powder
optical activity
[α]/D 26.0 to 34.0°°, c = 2% (solution in purified water, CALCULATED FOR DRIED SUBSTANCE)
mol wt
micellar avg mol wt 900-1300
aggregation number
2-3
loss
≤5% loss on drying
CMC
9-15 mM (20-25°C)
solubility
H2O: 0.1 M, H2O: 100 mg/mL
HLB
18
SMILES string
O.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3[C@H](O)CC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C
InChI
1S/C24H40O5.Na.H2O/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26;;/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29);;1H2/q;+1;/p-1/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-;;/m1../s1
InChI key
MUVVIYFKOVLQHL-RCVKHMDESA-M
General description
Application
- Optimization in Transdermal Drug Delivery: Applied in the formulation of ultra-elastic nanovesicles, sodium cholate hydrate enhances the bioavailability and anti-inflammatory efficacy of deflazacort, demonstrating its potential in transdermal drug delivery systems, which can be adapted for diagnostic purposes (Ali et al., 2021).
- Nanocarrier Formulations for IVDs: The study utilizes sodium cholate hydrate in the surface modification of bilosomes, serving as a functional and biocompatible nanocarrier for hybrid compounds, a method applicable to the formulation of innovative IVD reagents (Waglewska et al., 2020).
- IVD Reagent Formulation for Skin Delivery: Sodium cholate hydrate is featured in the development of nano-transfersomes for the delivery of antioxidants, showcasing its role in creating skin-applied diagnostic reagents that offer antioxidant and anti-aging effects (Avadhani et al., 2017).
- Sorting and Separation Techniques in Nanotechnology: Demonstrating the affinity-mediated sorting order reversal, sodium cholate hydrate is critical in density gradient ultracentrifugation techniques, highlighting its utility in the precise sorting and preparation of materials for diagnostic assays (Jang et al., 2016).
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hcodes
pcodes
Hazard Classifications
Aquatic Chronic 3
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)