C9911
(S)-(+)-カンプトテシン
≥90% (HPLC), powder, DNA topoisomerase I inhibitor
別名:
(S)-4-Ethyl-4-hydroxy-1H-pyrano-[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
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この商品について
製品名
(S)-(+)-カンプトテシン, ≥90% (HPLC), powder
Quality Segment
assay
≥90% (HPLC)
form
powder
mp
260 °C (dec.) (lit.)
solubility
chloroform/methanol (4:1): 5 mg/mL
antibiotic activity spectrum
neoplastics
mode of action
DNA synthesis | interferes, enzyme | inhibits
storage temp.
2-8°C
SMILES string
CC[C@@]1(O)C(=O)OCC2=C1C=C3N(Cc4cc5ccccc5nc34)C2=O
InChI
1S/C20H16N2O4/c1-2-20(25)14-8-16-17-12(7-11-5-3-4-6-15(11)21-17)9-22(16)18(23)13(14)10-26-19(20)24/h3-8,25H,2,9-10H2,1H3/t20-/m0/s1
InChI key
VSJKWCGYPAHWDS-FQEVSTJZSA-N
Gene Information
human ... TOP1(7150)
mouse ... Prkca(18750)
rat ... Sstr2(54305)
Biochem/physiol Actions
Features and Benefits
Other Notes
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Muta. 1B
保管分類
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges