바이오의약품 분야의 실시간 모니터링 및 제어

관련 자료

• White Paper: Workforce 4.0: The Long-Term Success of the Biopharmaceutical Industry

  A public-private approach to workforce 4.0 development, transitioning from conventional factories to “smart” manufacturing facilities.

• Application Note: In-Line Monitoring of CPPs and Capsid Titer in Upstream AAV Process with ProCellics™ Raman Analyzer

  Explore the ProCellics™ Raman Analyzer for in-line monitoring of critical process parameters (CPPs) and capsid titer during AAV production in Human Embryonic Kidney (HEK) cell bioreactors.

• Application Note: In-line Real-time Monitoring of CHO Cell Culture Process Parameters Using Raman Spectroscopy

  Cell culture processes are complex and highly variable and yet only a handful of key parameters such as temperature, pH, and dissolved oxygen (DO) are typically controlled in real time.

• Application Note: Implementation of Raman Spectroscopy for In-line Monitoring of CPPs of CHO Cell Perfusion Cultures

  This application note introduces a case study for the implementation of a Raman spectroscopy soft-sensor for in-line and real-time monitoring of critical process parameters (CPP) in mammalian perfusion cell cultures.

• Application Note: Seamless Integration of Glucose Control Using Raman Spectroscopy in CHO Cell Cultures

  Process analytical technology (PAT) and quality by design (QbD) are used in the biopharmaceutical industry to ensure quality is designed into a process and to achieve innovative quality improvements.

• Article: Influence of Cell Specific Parameters in a Dielectric Spectroscopy Conversion Model Used to Monitor Viable Cell Density in Bioreactors

  In the biopharmaceutical industry, the use of mammalian cells to produce therapeutic proteins is becoming increasingly widespread. Monitoring of these cultures via different analysis techniques is essential to ensure a good quality product while respecting good manufacturing practice (GMP) regulations.

• White Paper: Automated Aseptic Sampling for Accelerated Access to Process and Quality Data in Upstream Bioprocessing

  The biopharmaceutical market is experiencing increased demand for new medicines, reduction of costs, and new product classes, which is driving the need for increased flexibility and cost control measures in manufacturing.

• Data Sheet: MAST^® Autosampling Solution

  Current off-line sampling methods often present challenges related to sample source contamination, inadequate sample traceability and delivery, lengthy experimental turnaround times, and inconsistent results.

• Brochure: Process Development and Drug Manufacturing: Support Services

  We provide comprehensive services for drug development and manufacturing, including technical and regulatory expertise and process development support.