QBD10198
NHS-dPEG®12-biotin
동의어(들):
NHS-PEG Linker, Polyethylene glycol
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C41H72N4O18S
Molecular Weight:
941.09
UNSPSC Code:
12161502
PubChem Substance ID:
NACRES:
NA.22
InChI
1S/C41H72N4O18S/c46-36(4-2-1-3-35-40-34(33-64-35)43-41(50)44-40)42-8-10-52-12-14-54-16-18-56-20-22-58-24-26-60-28-30-62-32-31-61-29-27-59-25-23-57-21-19-55-17-15-53-13-11-51-9-7-39(49)63-45-37(47)5-6-38(45)48/h34-35,40H,1-33H2,(H,42,46)(H2,43,44,50)
InChI key
WOLXSUFTTIRQOU-UHFFFAOYSA-N
SMILES string
O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCCC1C2NC(NC2CS1)=O)=O)ON3C(CCC3=O)=O
assay
>90%
form
solid or viscous liquid
reaction suitability
reagent type: cross-linking reagent
reaction type: Biotinylations
reactivity: amine reactive
polymer architecture
shape: linear
functionality: monofunctional
shipped in
ambient
storage temp.
−20°C
Features and Benefits
NHS-dPEG®12-biotin is used extensively to label molecules that contain a free amine with biotin. The single molecular weight NHS-dPEG®12-biotin has a long spacer of precise length (47.6 Å) between the biotin moiety and the labeled molecule. This dPEG® spacer imparts a high degree of water solubility to the biotin label. For biotinylated peptides and proteins, the dPEG® spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin.
Legal Information
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Artem Babaian et al.
Cell reports, 31(5), 107611-107611 (2020-05-07)
The ribosome is an RNA-protein complex that is essential for translation in all domains of life. The structural and catalytic core of the ribosome is its ribosomal RNA (rRNA). While mutations in ribosomal protein (RP) genes are known drivers of
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