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Merck

1.03583

Parteck® SI 150 (Sorbitol)

EMPROVE® ESSENTIAL, Ph. Eur., BP, JP, NF, JSFA, E 420

동의어(들):

Parteck® Sorbitol, D-Glucitol

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C6H14O6
CAS 번호:
50-70-4
Molecular Weight:
182.17
UNSPSC Code:
12352201
E Number:
E420
MDL number:
MFCD00004708

주요 문서

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SMILES string

OC(C(O)C(O)CO)C(O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2

InChI key

FBPFZTCFMRRESA-UHFFFAOYSA-N

agency

BP, JP, JSFA, NF, Ph. Eur.

product line

EMPROVE® ESSENTIAL

form

fine powder

autoignition temp.

420 °C

particle size

(see specification)

pH

6-7 (20 °C, 100 g/L in H2O)

mp

94-96 °C

transition temp

flash point >100 °C

solubility

2350 g/L

density

1.49 g/cm3 at 20 °C

application(s)

liquid formulation
pharmaceutical
solid formulation

storage temp.

2-25°C

Quality Level

500

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관련 카테고리

General description

With formulation challenges in mind, we have used particle engineering technologies to develop functional excipients specifically for solid dosage forms. The products in our Parteck® portfolio feature unique particle properties tailored for excellent performance in tableting processes, for specific drug delivery technologies, or for solubility enhancement.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Parteck® SI excipient is a directly compressible sorbitol which combines excellent tableting behavior, resulting in very robust and shiny tablets, with a pleasant mouthfeel and taste. The unique and large surface area allows for a fast disintegration and dissolution, even at high tablet hardnesses and supports a good content uniformity of low dose API formulations. Parteck® SI excipient comes in a variety of particle sizes and qualities to meet the needs of a very wide range of applications.

Features and Benefits

  • Excellent direct compression properties
  • High dilution and adsorption capacity
  • Larger and highly structured surface area
  • Low hygroscopicity
  • Low amount of reducing sugars

Preparation Note

Storage temperature: no restrictions.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

저장 등급

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

시험 성적서(COA)

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문서

Solid Formulation Development Using Melt-based 3D Printing Technologies

3D printing can overcome challenges during formulation development, with a focus on enhancing API bioavailability in solid dispersions. Find out how in this technical article.

국제 무역 품목 번호

SKUGTIN
1.03583.250004022536961361
1.03583.902804022536936451

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