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Merck

1.41464

Parteck® MXP (Polyvinyl alcohol 4-88)

EMPROVE® ESSENTIAL, Ph. Eur., ChP, JPE, USP

동의어(들):

Parteck® Polyvinyl alcohol, PVA, PVOH

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
(C2H4O)n
CAS 번호:
9002-89-5
UNSPSC Code:
13111042
MDL number:
MFCD00081922

주요 문서

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기술 서비스
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도움 문의

InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

InChI key

IMROMDMJAWUWLK-UHFFFAOYSA-N

agency

ChP, JPE, Ph. Eur., USP

product line

EMPROVE® ESSENTIAL

form

fine powder

particle size

≤200 μm (d95)

mp

160-240 °C

application(s)

controlled release
pharmaceutical
solid formulation
solubility enhancement

storage temp.

15-25°C

Quality Level

500

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관련 카테고리

General description

With formulation challenges in mind, we have used particle engineering technologies to develop functional excipients specifically for solid dosage forms. The products in our Parteck® portfolio feature unique particle properties tailored for excellent performance in tableting processes, for specific drug delivery technologies, or for solubility enhancement.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Parteck® MXP excipient is a polyvinyl alcohol-based excipient specifically designed for hot-melt extrusion to increase the solubility of poorly water soluble APIs via stabilization of the amorphous solid state. Parteck® MXP enables stable and high drug loads and can be used for a broad range of poorly water soluble APIs and a variety of final dosage forms.

Features and Benefits

  • Superior supersaturation performance via precipitation inhibition
  • High thermostability up to 250°C, extending the potential application range
  • Stable high drug loads and suitability with a broad range of APIs
  • Flexible release kinetics
  • Compatible with several downstream processing capabilities, like direct compression, continuous manufacturing, thin film extrusion and 3D printing
  • Optimized powder properties for excellent performance in the HME process
  • Suitable polymer properties for HME, spray drying and 3D printing processes

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

저장 등급

11 - Combustible Solids

wgk

WGK 1

시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

문서

API Solubility and Dissolution Enhancement Via Formulation

Our overview of API solubility and dissolution enhancement methods can help you decide between the many options to take during formulation.

Improving API Solubility Using Spray Drying with Polyvinyl Alcohol

Discover how spray drying with polyvinyl alcohol enhances solubility for small and large molecule drugs and unlocks the potential of poorly soluble APIs.

Solid Formulation Development Using Melt-based 3D Printing Technologies

3D printing can overcome challenges during formulation development, with a focus on enhancing API bioavailability in solid dispersions. Find out how in this technical article.

관련 콘텐츠

국제 무역 품목 번호

SKUGTIN
1.41464.902504054839059896
1.41464.100004054839059889

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