41144
β-Alanine
analytical standard
동의어(들):
β-Ala, 3-Aminopropionic acid
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
NH2CH2CH2COOH
CAS 번호:
Molecular Weight:
89.09
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
203-536-5
Beilstein/REAXYS Number:
906793
MDL number:
InChI key
UCMIRNVEIXFBKS-UHFFFAOYSA-N
InChI
1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6)
grade
analytical standard
assay
≥98.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
analyte chemical class(es)
amino acids, peptides, proteins
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
impurities
≤0.3% water
color
white to off-white
mp
202 °C (dec.) (lit.)
application(s)
cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
format
neat
Quality Level
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General description
β-Alanine is a rate-limiting precursor of carnosine, a cytoplasmic dipeptide which is present in human skeletal muscles in high concentrations.
Application
β-Alanine may be used as a reference standard for the determination of β-alanine in:
- Potato tubers by gas chromatography-mass spectrometry (GC-MS).
- Human plasma, urine, and cerebrospinal fluid samples by liquid chromatography-tandem mass spectrometry (LC-MS/MS).
- Striatal microdialysis samples by high performance liquid chromatography-fluorescence detection (HPLC-FLD) with ortho-phthalaldehyde-mercaptoethanol derivatization.
- Fermented soybean paste, Cheonggukjang, by GC-MS operating in selected-ion monitoring (SIM) mode and principal component analysis (PCA).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
Endogenous β-amino acid that is a nonselective agonist at glycine receptors and a ligand for the G protein-coupled orphan receptor, TGR7 (MrgD). β-Alanine is a component of pantothenic acid.
β-Alanine, a β−amino acid, is a component of pantothenic acid and the rate-limiting amino acid in the biosynthesis of the histidinyl antioxidant dipeptides carnosine and anserine. Endogenous β-amino acid that is a nonselective agonist at glycine receptors and a ligand for the G protein-coupled orphan receptor, TGR7 (MrgD). β-Alanine flux plays a cytoprotective role by supporting the osmotic stability of marine organisms, preimplantation mouse embryos and mammalian cells exposed to hypoxic stress.
저장 등급
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
A rapid, sensitive method for quantitative analysis of underivatized amino acids by liquid chromatography-tandem mass spectrometry (LC-MS/MS)
Le A, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 944(1), 166-174 (2014)
Metabolite profiling of Cheonggukjang, a fermented soybean paste, during fermentation by gas chromatography-mass spectrometry and principal component analysis
Park MK, et al.
Food Chemistry, 122(4), 1313-1319 (2010)
Rapid and sensitive step gradient assays of glutamate, glycine, taurine and $\gamma$-aminobutyric acid by high-performance liquid chromatography-fluorescence detection with o-phthalaldehyde-mercaptoethanol derivatization with an emphasis on microdialysis samples
Piepponen TP and Skujins A
Journal of Chromatography. B, Biomedical Sciences and Applications, 757(2), 277-283 (2001)
Simultaneous analysis of metabolites in potato tuber by gas chromatography-mass spectrometry
Roessner U, et al.
The Plant Journal, 23(1), 131-142 (2000)
Effects of ?-alanine supplementation on exercise performance: a meta-analysis
Hobson RM, et al.
Amino Acids, 43(1), 25-37 (2012)
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