94425
Propionic acid
analytical standard
동의어(들):
Acid C3, Propanoic acid, Propanyl acid
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
CH3CH2COOH
CAS 번호:
Molecular Weight:
74.08
NACRES:
NA.24
PubChem Substance ID:
eCl@ss:
39021305
UNSPSC Code:
41116107
EC Number:
201-176-3
MDL number:
Beilstein/REAXYS Number:
506071
InChI key
XBDQKXXYIPTUBI-UHFFFAOYSA-N
InChI
1S/C3H6O2/c1-2-3(4)5/h2H2,1H3,(H,4,5)
SMILES string
CCC(O)=O
grade
analytical standard
vapor density
2.55 (vs air)
vapor pressure
2.4 mmHg ( 20 °C)
assay
≥99.5% (GC)
autoignition temp.
955 °F
shelf life
limited shelf life, expiry date on the label
expl. lim.
12.1 %
Quality Level
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
refractive index
n20/D 1.386
bp
141 °C (lit.)
mp
−24-−23 °C (lit.)
solubility
H2O: soluble
density
0.993 g/mL at 25 °C (lit.)
application(s)
cleaning products
cosmetics
environmental
flavors and fragrances
food and beverages
personal care
format
neat
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General description
Propionic acid (PA) is a naturally occurring carboxylic acid, which in its pure state exists as a colorless corrosive liquid with an unpleasant odor. It is miscible in water. Industrially it is produced by hydrocarboxylation of ethylene in presence nickel carbonyl as a catalyst. PA has been found to reduce food intake, lower the fatty acids content in plasma and liver, might improve tissue insulin sensitivity and exerts immunosuppressive actions. Propionic acid is an excellent raw material as it is stable, cheap and safe and can even be used as a food additive.
Application
Propionic acid has been used as a standard for the gas chromatogrsphic (GC) analysis of short chain fatty acids obatined from Lactobacillus reuteri SK24.003 and α-D-glucan.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - STOT SE 3
target_organs
Respiratory system
저장 등급
3 - Flammable liquids
wgk
WGK 1
flash_point_f
129.2 °F - closed cup
flash_point_c
54 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Structural elucidation and in vitro fermentation of extracellular ?-d-glucan from Lactobacillus reuteri SK24. 003
Miao M, et al.
Bioactive Carbohydrates and Dietary Fibre, 6(2), 109-116 (2015)
Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms
Sa'ad, H., et al.
Molecular and Cellular Biology, 1801 (11), 1175-1183 (2010)
Nucleophilic ?-Carbon Activation of Propionic Acid as a 3-Carbon Synthon by Carbene Organocatalysis
Jin, Zhichao, et al.
Chemistry?A European Journal , 21 (26), 9360-9363 (2015)
Livia H Morais et al.
Current biology : CB, 30(19), 3761-3774 (2020-08-22)
Birth by Caesarean (C)-section impacts early gut microbiota colonization and is associated with an increased risk of developing immune and metabolic disorders. Moreover, alterations of the microbiome have been shown to affect neurodevelopmental trajectories. However, the long-term effects of C-section
Sa'ad H Al-Lahham et al.
Biochimica et biophysica acta, 1801(11), 1175-1183 (2010-08-10)
Undigested food is fermented in the colon by the microbiota and gives rise to various microbial metabolites. Short-chain fatty acids (SCFA), including acetic, propionic and butyric acid, are the principal metabolites produced. However, most of the literature focuses on butyrate
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