01148
Sodium fluoride
puriss., meets analytical specification of Ph. Eur., BP, USP, 98.5-100.5% (calc. to the dried substance)
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제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
NaF
CAS 번호:
Molecular Weight:
41.99
UNSPSC Code:
12352302
eCl@ss:
38050104
PubChem Substance ID:
EC Number:
231-667-8
NACRES:
NA.21
MDL number:
Assay:
98.5-100.5% (calc. to the dried substance)
Form:
powder
vapor pressure
1.4 mmHg ( 0 °C)
Quality Level
grade
puriss.
assay
98.5-100.5% (calc. to the dried substance)
form
powder
quality
meets analytical specification of Ph. Eur., BP, USP
impurities
acidity or alkalinity, complies, organic volatile impurities, complies (GC), residual solvents, complies, ≤0.002% heavy metals (as Pb), ≤0.1% free alkali (as NaOH), ≤0.2% free acid (as HF), ≤0.2% sodium hexafluorosilicate (Na2SiF6)
loss
≤0.5% loss on drying, 150 °C
mp
993 °C (lit.)
anion traces
chloride (Cl-): ≤100 mg/kg, sulfate (SO42-): ≤200 mg/kg
cation traces
Fe: ≤50 mg/kg
suitability
complies for appearance of solution
SMILES string
[F-].[Na+]
InChI
1S/FH.Na/h1H;/q;+1/p-1
InChI key
PUZPDOWCWNUUKD-UHFFFAOYSA-M
General description
Sodium fluoride (NaF) is a metallic halide. It has been reported as dental caries preventive agent. It is the most widely employed preservative for glucose in blood. It has been reported to stabilize hepatic microsomal glucose-6-P phosphohydrolase enzyme.
Application
Sodium fluoride may be employed as fluorination agent in the synthesis of aromatic and aliphatic fluorides, via metathesis. It may be used to prepare the lysis buffer.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2
supp_hazards
flash_point_f
Not applicable
flash_point_c
Not applicable
저장 등급
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
A J Lange et al.
The Journal of biological chemistry, 261(1), 101-107 (1986-01-05)
Stabilization and inhibition of hepatic microsomal glucose-6-P phosphohydrolase (EC 3.1.3.9) by F- requires the presence of Al3+ ions. At millimolar concentrations, reagent grade NaF inhibited glucose-6-P hydrolysis and protected the enzyme against inactivation induced by heat in the presence of
J G Drachman et al.
The Journal of biological chemistry, 270(10), 4979-4982 (1995-03-10)
c-Mpl is a member of the cytokine receptor superfamily, expressed primarily on hematopoietic cells. Recently, the c-Mpl ligand was cloned and found to have thrombopoietic activity. In this paper we report that ligand binding induced tyrosine phosphorylation in BaF3 cells
Synthesis of fluorides by metathesis with sodium fluoride.
Tullock CW and Coffman DD.
The Journal of Organic Chemistry, 25(11), 2016-2019 (1960)