B3398
Anti-Human IgG2−Biotin antibody, Mouse monoclonal
clone HP-6014, purified from hybridoma cell culture
동의어(들):
Monoclonal Anti-Human IgG2
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
biotin conjugate
Clone:
HP-6014, monoclonal
Application:
direct ELISA
Species reactivity:
human
Citations:
15
Technique(s):
direct ELISA: 1:30,000
제품 이름
Anti-Human IgG2−Biotin antibody, Mouse monoclonal, clone HP-6014, purified from hybridoma cell culture
biological source
mouse
conjugate
biotin conjugate
antibody form
purified from hybridoma cell culture
antibody product type
secondary antibodies
clone
HP-6014, monoclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
direct ELISA: 1:30,000
isotype
IgG1
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
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관련 카테고리
Application
Monoclonal Anti-Human IgG2−Biotin antibody produced in mouse has been used in indirect enzyme linked immunosorbent assay (ELISA) and immunoblot.
Biochem/physiol Actions
IgG provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
Low IgG2 levels were found in patients with systemic lupus erythematosus (SLE) and juvenile diabetes melitus.
The antibody is specific for human IgG2 and is non-reactive with other IgG subclasses. This clone has been singled out as the most widely applicable IgG2 specific monoclonal antibody by the IUIS/WHO study.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Monoclonal Anti-Human IgG2 (mouse IgG1 isotype) is derived from the hybridoma (HP-60141 ) produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. IgG is the most abundant serum immunoglobulins of the immune system. IgG2 is a subtype of IgG. IgG is secreted by B cells and is found in blood and extracellular fluids.
Physical form
Solution in 0.01 M phosphate buffered saline pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide
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저장 등급
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Immunoglobulin subclass deficiency
Hanson L A, et al.
The Pediatric Infectious Disease Journal, 7, 7-21 (1988)
Nadia Ben Nouir et al.
Journal of clinical microbiology, 46(5), 1631-1640 (2008-03-28)
Echinococcus granulosus protoscolex soluble somatic antigens (PSSAs) were assessed for their prognostic value in the serological follow-up of young patients treated for cystic echinococcosis (CE), compared to conventional hydatid fluid (HF) antigen. Based on different clinical courses and outcome of
Esmail Mohamad El-Fakharany et al.
Experimental and therapeutic medicine, 13(4), 1313-1320 (2017-04-18)
Hepatitis C virus (HCV) infection represents a world health problem and no protective vaccine or effective drug currently exists. For economic reasons, many patients use traditional medicines to control the infection. In Egypt, camel milk is one of the traditional
Marianna Spatola et al.
Neurology, 95(22), e3012-e3025 (2020-09-16)
To clinically characterize patients with anti-metabotropic glutamate receptor (mGluR) 1 encephalitis, to identify prognostic factors, and to study the immunoglobulin G (IgG) subclasses and effects of antibodies on neuronal mGluR1 clusters. Clinical information on new and previously reported patients was
Elana R Shaw et al.
Current protocols, 2(8), e511-e511 (2022-08-18)
Autoantibodies (autoAbs) that neutralize type 1 interferons (T1IFNs) are a major risk factor associated with developing critical COVID-19 disease and are most commonly found in individuals over age 70 and in patients with genetic or acquired thymic defects. Swift identification
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