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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C14H10N3Na4O12PS2 · xH2O
CAS 번호:
Molecular Weight:
599.31 (anhydrous basis)
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
제품 이름
Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate, solid, ≥98% (HPLC)
InChI
1S/C14H14N3O12PS2.4Na.H2O/c1-7-13(19)9(5-18)10(6-29-30(20,21)22)14(15-7)17-16-11-3-2-8(31(23,24)25)4-12(11)32(26,27)28;;;;;/h2-5,19H,6H2,1H3,(H2,20,21,22)(H,23,24,25)(H,26,27,28);;;;;1H2/q;4*+1;/p-4/b17-16+;;;;;
SMILES string
O.[Na+].[Na+].[Na+].[Na+].Cc1nc(\N=N\c2ccc(cc2S([O-])(=O)=O)S([O-])(=O)=O)c(COP([O-])([O-])=O)c(C=O)c1O
InChI key
JTTDHFFNVGHDLN-YDTRVRFHSA-J
assay
≥98% (HPLC)
form
solid
color
red to orange
solubility
H2O: >10 mg/mL
storage temp.
−20°C
Quality Level
Gene Information
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Biochem/physiol Actions
Non-selective P2 purinoceptor antagonist which blocks responses at both pre- and post-junctional sites.
Disclaimer
Light sensitive
Features and Benefits
This compound is featured on the P2 Receptors: P2X Ion Channel Family and P2 Receptors: P2Y G-Protein Family pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Marian T Namovic et al.
Current protocols in pharmacology, Chapter 9, Unit 9-Unit 9 (2012-06-12)
Adenosine triphosphate (ATP) activates two receptor superfamilies, metabotropic P2Y and ionotropic P2X receptors. The P2X receptors are nonselective cation channels that are widely expressed on excitable cells including neurons, glia, and smooth muscle cells. The protocols in this unit are
Christian Kranjec et al.
Scientific reports, 11(1), 13909-13909 (2021-07-08)
Bacteriocins are ribosomally-synthesized antimicrobial peptides, showing great potential as novel treatment options for multidrug-resistant pathogens. In this study, we designed a novel hybrid bacteriocin, Hybrid 1 (H1), by combing the N-terminal part and the C-terminal part of the related bacteriocins
G Lambrecht et al.
European journal of pharmacology, 217(2-3), 217-219 (1992-07-07)
We have characterized PPADS (pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid) as a novel antagonist which selectively blocks P2 purinoceptor-mediated responses in rabbit vas deferens at pre- and postjunctional sites. PPADS did not interact with alpha 1-adrenoceptors, muscarinic M2 and M3 receptors, histamine H1 and
Déborah Lécuyer et al.
Frontiers in immunology, 14, 1270081-1270081 (2023-11-03)
Purinergic receptors and NOD-like receptor protein 3 (NLRP3) inflammasome regulate inflammation and viral infection, but their effects on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection remain poorly understood. Here, we report that the purinergic receptor P2X7 and NLRP3 inflammasome
Lisa Felix et al.
Cells, 9(1) (2020-01-08)
In the neonate forebrain, network formation is driven by the spontaneous synchronized activity of pyramidal cells and interneurons, consisting of bursts of electrical activity and intracellular Ca2+ oscillations. By employing ratiometric Na+ imaging in tissue slices obtained from animals at
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