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ABT406 Anti-LRRFIP1 Antibody

Anti-LRRFIP1 Antibody detects level of LRRFIP1 & has been published & validated for use in LRRFIP1.

Anti-LRRFIP1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: Cytoskeleton Gene Symbol: LRRFIP1, GCF2, TRIP UniProt Number: Q32MZ4
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ABT406
100 µg  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABT406
      DescriptionAnti-LRRFIP1 Antibody
      Alternate Names
      • Leucine-rich repeat flightless-interacting protein 1
      • LRR FLII-interacting protein 1
      • GC-binding factor 2
      • TAR RNA-interacting protein
      Background InformationLeucine-rich repeat flightless-interacting protein 1 (LRR FLII-interacting protein 1), also known as GC-binding factor 2 or TAR RNA-interacting protein, and encoded by the gene name LRRFIP1 or GCF2 or TRIP, is a transcriptional repressor that mainly plays a cytoskeletal role. LRRFIP1 is primarily localized in the cytoplasm and preferentially binds to GC-rich dsDNA, but will also bind directly to dsRNA as well. The RNA binding domain encompasses a lysine-rich motif. LRRFIP1 interacts with the mammalian Flightless I (Fli-I) and is a key component in the cytoskeletal regulation of platelet function. LRRFIP1 and the related protein LRRFIP2 may modulate canonical WNT signaling and mediate the IRF3-induced production of type I interferon via a β-catenindependent pathway.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-LRRFIP1 Antibody detects level of LRRFIP1 & has been published & validated for use in LRRFIP1.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenKLH-conjugated synthetic peptide corresponding to human LRRFIP1.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • LRRFIP1
      • GCF2
      • TRIP
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~85 kDa observed. Uncharacterized bands may be observed in some lysate(s). Uniprot describes 4 isoforms produced by alternative splicing ranging between ~73 kDa and ~89 kDa.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human colon tissue lysate.

      Western Blotting Analysis: 1 μg/mL of this antibody detected LRRFIP1 in human colon tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABT406 04053252953064