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MABD50 Anti-MyT1L Antibody, clone 20B4.1

Detect the MyT1L protein using this Anti-MyT1L, clone 20B4.1 validated for use in WB & IHC.

Anti-MyT1L Antibody, clone 20B4.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: MYT1L UniProt Number: Q9UL68
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MABD50
100 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, HWB, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABD50
      DescriptionAnti-MyT1L Antibody, clone 20B4.1
      Alternate Names
      • Myelin transcription factor 1-like protein
      • MyT1-L
      • MyT1L
      Background InformationMyelin transcription factor 1-like (Myt1L) is a zinc finger protein belonging to the myelin transcription factor 1 family. It influences the expression of genes involved in the proliferation and differentiation of oligodentrocytes in the developing central nervous system. Myt1L may contribute to the silencing of its target genes by recruiting Sin3B that binds to and enhances the activity of HDAC. Several studies have implicated Myt1L in the pathogenesis of complex psychiatric diseases such as schizophrenia, major depressive disorder, and bipolar disorder.
      References
      Product Information
      FormatPurified
      Control
      • Mouse E17 spinal cord tissue lysate
      PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect the MyT1L protein using this Anti-MyT1L, clone 20B4.1 validated for use in WB & IHC.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:10-1:50 dilution from a representative lot detected MyT1L in human pons, mouse frontal cortex, and mouse hippocampus tissues.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human MyT1L.
      Clone20B4.1
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgG1κ
      Species Reactivity
      • Mouse
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • MYT1L
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~170 kDa observed. Uniprot describes three isoforms at 21, 126, and 133 kDa.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in mouse E17 spinal cord tissue lysate.

      Western Blot Analysis: A 1:1.000 dilution of this antibody detected MyT1L on 10 µg of mouse E17 spinal cord tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABD50 04053252648199

      Documentation

      Anti-MyT1L Antibody, clone 20B4.1 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-MyT1L Antibody, clone 20B4.1 Certificates of Analysis

      TitleLot Number
      Anti-MyT1L, clone 20B4.1 - 2424835 2424835
      Anti-MyT1L, clone 20B4.1 - 2090955 2090955
      Anti-MyT1L, clone 20B4.1 - 2161191 2161191
      Anti-MyT1L, clone 20B4.1 - 2514232 2514232
      Anti-MyT1L, clone 20B4.1 - 3229390 3229390
      Anti-MyT1L, clone 20B4.1 - 3487597 3487597
      Anti-MyT1L, clone 20B4.1 - Q2021130 Q2021130
      Anti-MyT1L, clone 20B4.1 Monoclonal Antibody 2943590
      Anti-MyT1L, clone 20B4.1 Monoclonal Antibody 2866727
      Anti-MyT1L, clone 20B4.1 Monoclonal Antibody 2920707

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies