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AB15300 Anti-NECL-1 Antibody

Detect NECL-1 using this Anti-NECL-1 Antibody validated for use in IH & WB.

Anti-NECL-1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Neurofilament & Neuron Metabolism Gene Symbol: CADM3, IGSF4B, NECL1, SYNCAM3, TSLL1 UniProt Number: Q8N126
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AB15300
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MIHC, WBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB15300
      Trade Name
      • Chemicon
      DescriptionAnti-NECL-1 Antibody
      Background InformationNectins are immunoglobulin superfamily adhesion molecules that participate in the organization of epithelial and endothelial junctions. Human and mouse NECL1 share 87.3% identity at the amino acid level (1). NECL1 contains an ectodomain made of three immunoglobulin-like domains, and a cytoplasmic region homologous to those of glycophorin C and contactin-associated protein. NECL1 predominantly expressed in the central nervous system, mainly in neuronal cell bodies in a variety of brain regions including the cerebellum, cerebral cortex and hippocampus. NECL1 localizes to the cell-cell junctions and recruits protein 4.1N to the plasma membranes through its C-terminus, thus may regulate the function of the cell-cell junction.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Tested on Adult mouse brain lysate
      PresentationPurified Antibody in PBS with 0.1% NaN3
      Quality LevelMQ100
      Applications
      ApplicationDetect NECL-1 using this Anti-NECL-1 Antibody validated for use in IH & WB.
      Key Applications
      • Immunohistochemistry
      • Western Blotting
      Application NotesWestern Blot Analysis: NECL-1 can be detected at 1/500 dilution. Testing at further dilution was not conducted.

      Immunohistochemistry: 1:50 to 1:1000 straight dilution of Cat. # AB15301 was tested on human medulla oblongata tissue.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenSynthetic Peptide
      HostRabbit
      SpecificityNECL-1
      Species Reactivity
      • Mouse
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • CADM3
      • IGSF4B
      • NECL1
      • SYNCAM3
      • TSLL1
      Purification MethodImmunoAffinity Purified
      UniProt Number
      Molecular Weight43 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      AB15300 04053252589324