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ABC327 Anti-PD-L2 Antibody

Anti-PD-L2 Antibody is a highly specific rabbit polyclonal antibody, that targets Programmed cell death 1 ligand 1 & has been tested in western blotting, IHC (Paraffin) & Immunofluorescence.

Anti-PD-L2 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2 UniProt Number: Q9BQ51
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ABC327
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MWB, IH(P), IFRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABC327
      DescriptionAnti-PD-L2 Antibody
      Alternate Names
      • Programmed cell death 1 ligand 2
      • PD-1 ligand 2
      • PD-L2
      • PDCD1 ligand 2
      • Programmed death ligand 2
      • Butyrophilin B7-DC
      • B7-DC
      • CD273
      Background InformationProgrammed cell death ligand 2 (PD-L2, PD-1 ligand 2, PDCD1 ligand 2), also known as Butyrophilin B7-DC (B7-DC), is a member of the BTN/MOG family and immunoglobulin superfamily which is thought to act as a negative regulator of T cell activation. PD-L2 may play a role in stimulating an immunogenic response through an alternative receptor from PD-1. PD-L2 is highly expressed in heart, placenta, pancreas, lung, and liver and weakly expressed in spleen, lymph nodes, and thymus.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Raji cell lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-PD-L2 Antibody is a highly specific rabbit polyclonal antibody, that targets Programmed cell death 1 ligand 1 & has been tested in western blotting, IHC (Paraffin) & Immunofluorescence.
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      • Immunofluorescence
      Application NotesImmunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected PD-L2 in mouse brain tissue.

      Immunofluorescence Analysis: 20 μg/mL from a representative lot detected PD-L2 in mouse brain cells.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human PD-L2.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody only recognizes the largest isoform at ~31 kDa.
      Species Reactivity
      • Human
      • Mouse
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • PDCD1LG2
      • B7DC
      • CD273
      • PDCD1L2
      • PDL2
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~31 kDa observed. Uniprot describes 2 isoforms at ~21 kDa and one isoform at ~31 kDa. Uncharacterized bands may appear in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in Raji cell lysate

      Western Blotting Analysis: 2 µg/mL of this antibody detected PD-L2 in 15 µg of Raji cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABC327 04053252901331

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies