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ABE431 Anti-PTBP2 Antibody

Anti-PTBP2 Antibody is a highly specific rabbit polyclonal antibody, that targets Polypyrimidine tract-binding protein 2 & has been tested in western blotting & IP.

Anti-PTBP2 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Transcription Factors Gene Symbol: PTBP2, NPTB, PTB, PTBLP UniProt Number: Q9UKA9
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ABE431
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RWB, IPRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABE431
      DescriptionAnti-PTBP2 Antibody
      Alternate Names
      • Polypyrimidine tract-binding protein 2
      • Neural polypyrimidine tract-binding protein
      • Neurally-enriched homolog of PTB
      • PTB-like protein
      Background InformationPolypyrimidine tract-binding protein 2 (PTBP2) is also known as Neural polypyrimidine tract-binding protein, Neurally-enriched homolog of PTB and PTB-like protein. PTBP2 is a RNA-binding protein which targets intronic polypyrimidines and negatively regulates pre-mRNA, exonic splicing. PTBP2 also has a role in translational regulation. PTBP2 is mainly expressed in brain, but is also found in heart and skeletal muscle. Isoforms 1 and 2 are specifically expressed in neuronal tissues.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Human cortex tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-PTBP2 Antibody is a highly specific rabbit polyclonal antibody, that targets Polypyrimidine tract-binding protein 2 & has been tested in western blotting & IP.
      Key Applications
      • Western Blotting
      • Immunoprecipitation
      Application NotesWestern Blotting Analysis: 0.5 µg/mL from a representative lot detected PTBP2 in 10 µg of rat brain cortex tissue lysate.
      Immunoprecipitation Analysis: 10ug from a representative lot immunoprecipitated PTBP2 in 500 µg of P19 cell lysate.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the N-terminus of human PTBP2.
      EpitopeN-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes the N-terminus of PTBP2.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Species Reactivity NoteDemonstrated to react with Human, Mouse, and Rat. Predicted to react with Bovine, Canine, Rhesus Macaque, and Gorilla based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • PTBP2
      • NPTB
      • PTB
      • PTBLP
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~57 kDa observed. Uncharacterized band(s) may appear in some lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human cortex tissue lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected PTBP2 in 10 µg of human cortex tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABE431 04053252914027