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AP1157 Anti-TNFRSF1B Rabbit pAb

This Anti-TNFRSF1B Rabbit pAb is validated for use in Immunoblotting for the detection of TNFRSF1B.

Anti-TNFRSF1B Rabbit pAb MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-Tumor Necrosis Factor Receptor Superfamily 1B

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AP1157
  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityHostAntibody Type
      H, MRbPolyclonal Antibody
      Description
      OverviewRecognizes the ~60 kDa TNFRSF1B protein in mouse testes tissue.
      Catalogue NumberAP1157
      Brand Family Calbiochem®
      SynonymsAnti-Tumor Necrosis Factor Receptor Superfamily 1B
      Application Data
      Detection of mouse TNFRSF1B by immunoblotting. Sample: Whole tissue extracy from mouse testes. Primary antibody: Anti-TNFRSF1B Rabbit pAb (Cat. No. AP1157) (1-5 µg/ml). Detection: chemiluminescence.
      References
      Product Information
      FormLiquid
      FormulationIn PBS, pH 7.2.
      Negative control293T cells
      Positive controlMouse testes tissue
      PreservativeNone
      Quality LevelMQ100
      Applications
      Key Applications Immunoblotting (Western Blotting)
      Application NotesImmunoblotting (1-5 µg/ml)
      Application CommentsVariables associated with assay conditions will dictate the proper working dilution.
      Biological Information
      ImmunogenFull-length, human TNFRSF1B (aa 1-461)
      ImmunogenHuman
      HostRabbit
      IsotypeIgG
      Species Reactivity
      • Human
      • Mouse
      Antibody TypePolyclonal Antibody
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Regulatory Review
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      AP1157 0

      Documentation

      Anti-TNFRSF1B Rabbit pAb SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-TNFRSF1B Rabbit pAb Certificates of Analysis

      TitleLot Number
      AP1157
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision19-October-2010 RFH
      SynonymsAnti-Tumor Necrosis Factor Receptor Superfamily 1B
      ApplicationImmunoblotting (1-5 µg/ml)
      Application Data
      Detection of mouse TNFRSF1B by immunoblotting. Sample: Whole tissue extracy from mouse testes. Primary antibody: Anti-TNFRSF1B Rabbit pAb (Cat. No. AP1157) (1-5 µg/ml). Detection: chemiluminescence.
      DescriptionPurified rabbit polyclonal antibody. Recognizes the ~60 kDa TNFRSF1B protein.
      BackgroundTNFRSF1B is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signaling is unknown; however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
      HostRabbit
      Immunogen speciesHuman
      ImmunogenFull-length, human TNFRSF1B (aa 1-461)
      IsotypeIgG
      Specieshuman, mouse
      Positive controlMouse testes tissue
      Negative control293T cells
      FormLiquid
      FormulationIn PBS, pH 7.2.
      PreservativeNone
      CommentsVariables associated with assay conditions will dictate the proper working dilution.
      Storage Avoid freeze/thaw
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Regulatory Review