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341215 Exotoxin A, Pseudomonas aeruginosa - CAS 91262-95-2 - Calbiochem

Exotoxin A, Pseudomonas aeruginosa, CAS 91262-95-2, inhibits protein synthesis through ADP-ribosylation of elongation factor 2. Shown to be cytopathic for a number of cell lines.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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341215
  
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      Overview

      Replacement Information

      Key Spec Table

      CAS #
      91262-95-2
      Description
      Overview

      This product has been discontinued.



      Shown to inhibit protein synthesis through ADP-ribosylation of elongation factor 2. Cytopathic for a number of cell lines and exhibits toxicity in animals. Has enzymatic activity identical to that of diphtheria toxin, however it has distinct target-cell specificities and is immunologically unrelated.
      Catalogue Number341215
      Brand Family Calbiochem®
      References
      ReferencesPrentice, G.A., and Merrill, A.R. 1999. Anal. Biochem. 272, 216.
      Product Information
      CAS number91262-95-2
      ATP CompetitiveN
      FormLyophilized
      FormulationSolid lyophilized from 150 mM NaCl, 10 mM sodium phosphate buffer, pH 7.5.
      ReversibleN
      Quality LevelMQ100
      Applications
      ApplicationExotoxin A, Pseudomonas aeruginosa, CAS 91262-95-2, inhibits protein synthesis through ADP-ribosylation of elongation factor 2. Shown to be cytopathic for a number of cell lines.
      Biological Information
      Primary TargetADP-ribosylation of elongation factor 2
      PuritySingle band by SDS-PAGE; single precipitin band by immunodiffusion
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSLF2991000
      Safety Information
      R PhraseR: 26/27/28

      Very toxic by inhalation, in contact with skin and if swallowed.
      S PhraseS: 22-36/37/39-45

      Do not breathe dust.
      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Highly Toxic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage +2°C to +8°C
      Do not freeze Yes
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 2 weeks at 4°C or for up to 6 months at -20°C.
      Canadian export regulations Due to the country and/or U.S. state of origin of the animal material used in this product, this product may not be exported to Canada.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      341215 0

      Documentation

      Exotoxin A, Pseudomonas aeruginosa - CAS 91262-95-2 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Exotoxin A, Pseudomonas aeruginosa - CAS 91262-95-2 - Calbiochem Certificates of Analysis

      TitleLot Number
      341215

      References

      Reference overview
      Prentice, G.A., and Merrill, A.R. 1999. Anal. Biochem. 272, 216.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision24-June-2008 RFH
      DescriptionShown to inhibit protein synthesis through ADP-ribosylation of elongation factor 2. Cytopathic for a number of cell lines and exhibits toxicity in animals. Has enzymatic activity identical to that of diphtheria toxin; however, it has distinct target-cell specificity and is immunologically unrelated.
      FormLyophilized
      FormulationSolid lyophilized from 150 mM NaCl, 10 mM sodium phosphate buffer, pH 7.5.
      CAS number91262-95-2
      RTECSLF2991000
      PuritySingle band by SDS-PAGE; single precipitin band by immunodiffusion
      SolubilityH₂O
      Storage +2°C to +8°C
      Do Not Freeze Yes
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 2 weeks at 4°C or for up to 6 months at -20°C.
      Toxicity Highly Toxic
      ReferencesPrentice, G.A., and Merrill, A.R. 1999. Anal. Biochem. 272, 216.