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344905 FURA 2/AM - CAS 108964-32-5 - Calbiochem

Overview

Replacement Information

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344905-1MG
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      Plastic ampoule 1 mg
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      344905-1SET
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          344905-5MG
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              Plastic ampoule 5 mg
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              Description
              OverviewCell-permeable ester form of FURA 2. Note: 1 set = 10 x 100 µg.
              PLURONIC® F-127, PROTEIN GRADE® Detergent (Cat. No. 540025, available separately) is a mild, low-toxicity detergent that can aid in the solubilization of FURA 2/AM.
              Catalogue Number344905
              Brand Family Calbiochem®
              Synonyms1-[2-(5-Carboxyoxazol-2-yl)-6-aminobenzofuran-5-oxy]-2-(2ʹ-amino-5ʹ-methylphenoxy)-ethane-N,N,NʹNʹ-tetraacetic Acid Pentaacetoxymethyl Ester
              References
              ReferencesDavis, M.J., et al. 1992. Am. J. Physiol. 263, H1292.
              Rao, G.H., et al. 1992. Biochem. Med. Metab. Biol. 47, 226.
              Schwartz, Y., et al. 1992. Endocrinology 131, 772.
              Ward, C.A., and Moffat, M.P. 1992. J. Mol. Cell. Cardiol. 24, 937.
              Janconi, M.E., et al. 1990. J. Cell Biol. 110, 1555.
              Tsien, R.Y. 1980. Biochemistry 19, 2396.
              Product Information
              CAS number108964-32-5
              ATP CompetitiveN
              FormYellow solid
              Hill FormulaC₄₄H₄₇N₃O₂₄
              Chemical formulaC₄₄H₄₇N₃O₂₄
              ReversibleN
              Structure formula ImageStructure formula Image
              Quality LevelMQ100
              Applications
              Biological Information
              Primary TargetRatiometric calcium indicator
              Purity≥95% by HPLC.
              Physicochemical Information
              Cell permeableY
              Emission max.
              Excitation max.
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              Safety Information
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Standard Handling
              Storage -20°C
              Protect from Light Protect from light
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) under an inert gas. Stock solutions are stable for up to 1 month at -20°C.
              Packaging Information
              Packaged under inert gas Packaged under inert gas
              Transport Information
              Supplemental Information
              Specifications
              Global Trade Item Number
              Catalogue Number GTIN
              344905-1MG 04055977214895
              344905-1SET 04055977214901
              344905-5MG 04055977214918

              Documentation

              FURA 2/AM - CAS 108964-32-5 - Calbiochem SDS

              Title

              Safety Data Sheet (SDS) 

              FURA 2/AM - CAS 108964-32-5 - Calbiochem Certificates of Analysis

              TitleLot Number
              344905

              References

              Reference overview
              Davis, M.J., et al. 1992. Am. J. Physiol. 263, H1292.
              Rao, G.H., et al. 1992. Biochem. Med. Metab. Biol. 47, 226.
              Schwartz, Y., et al. 1992. Endocrinology 131, 772.
              Ward, C.A., and Moffat, M.P. 1992. J. Mol. Cell. Cardiol. 24, 937.
              Janconi, M.E., et al. 1990. J. Cell Biol. 110, 1555.
              Tsien, R.Y. 1980. Biochemistry 19, 2396.

              Brochure

              Title
              Caspases and other Apoptosis Related Tools Brochure
              Fluorescent Calcium Probes Technical Bulletin
              Data Sheet

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision27-June-2008 RFH
              Synonyms1-[2-(5-Carboxyoxazol-2-yl)-6-aminobenzofuran-5-oxy]-2-(2ʹ-amino-5ʹ-methylphenoxy)-ethane-N,N,NʹNʹ-tetraacetic Acid Pentaacetoxymethyl Ester
              DescriptionCell permeant ester form of FURA 2 (Cat. No. 344900). The active dye is rapidly released in the cell by cytoplasmic esterases. Fluorescent calcium chelator (Kd = 224 nM) that offers 30 times greater fluorescence intensity than QUIN 2 (Cat. No. 551826). Can be used as a probe in many cellular systems, including cardiac myocytes, vascular smooth muscle cells, and medullary collecting tubules. Spectral properties in the presence of low calcium concentrations (excitation max.: 362 nm, emission max.: 512 nm) differ from those during high calcium conditions (excitation max.: 335 nm, emission max.: 505 nm). Note: 1 set = 10 x 100 µg.
              FormYellow solid
              Intert gas (Yes/No) Packaged under inert gas
              CAS number108964-32-5
              Chemical formulaC₄₄H₄₇N₃O₂₄
              Structure formulaStructure formula
              Purity≥95% by HPLC.
              SolubilityDMSO (10 mg/ml). Further dilute with aqueous buffers just prior to use.
              Storage Protect from light
              -20°C
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) under an inert gas. Stock solutions are stable for up to 1 month at -20°C.
              Toxicity Standard Handling
              ReferencesDavis, M.J., et al. 1992. Am. J. Physiol. 263, H1292.
              Rao, G.H., et al. 1992. Biochem. Med. Metab. Biol. 47, 226.
              Schwartz, Y., et al. 1992. Endocrinology 131, 772.
              Ward, C.A., and Moffat, M.P. 1992. J. Mol. Cell. Cardiol. 24, 937.
              Janconi, M.E., et al. 1990. J. Cell Biol. 110, 1555.
              Tsien, R.Y. 1980. Biochemistry 19, 2396.

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              Categories

              Life Science Research > Inhibitors and Biochemicals