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356780 Glycyrrhizin, Ammonium Salt - CAS 53956-04-0 - Calbiochem

Inhibits replication, adsorption, and penetration of severe acute respiratory syndrome-associated coronavirus (SARS-CV). It is allso a known 11β-hydroxysteroid dehydrogenase type 2 (11-HSD2) inhibitor.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Glycyrrhizic Acid, NH₄+

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356780
  
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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      53956-04-0C₄₂H₆₁O₁₆ • NH₄
      Description
      OverviewA triterpenoid saponin isolated from liquorice roots that displays antiviral and anti-tumor activities. Inhibits replication, adsorption, and penetration of severe acute respiratory syndrome-associated coronavirus (SARS-CV), presumably via its ability to upregulate nitric oxide synthase activity. Reported to block the growth of other viruses, including herpes virus, and helps restore liver functions in patients with hepatitis C. It is allso a known 11β-hydroxysteroid dehydrogenase type 2 (11-HSD2) inhibitor.
      Catalogue Number356780
      Brand Family Calbiochem®
      SynonymsGlycyrrhizic Acid, NH₄+
      References
      ReferencesCinatl, J., et al. 2003. Lancet 361, 2045.
      Tanahashi, T., et al. 2002. J. Steroid Biochem. Mol. Biol. 80, 441.
      Kondo, Y., and Takano, F. 1994. Biol. Pharm. Bull. 17, 759.
      Product Information
      CAS number53956-04-0
      FormWhite to off-white solid
      Hill FormulaC₄₂H₆₁O₁₆ • NH₄
      Chemical formulaC₄₂H₆₁O₁₆ • NH₄
      Hygroscopic Hygroscopic
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSLZ6500000
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      356780 0

      Documentation

      Glycyrrhizin, Ammonium Salt - CAS 53956-04-0 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Glycyrrhizin, Ammonium Salt - CAS 53956-04-0 - Calbiochem Certificates of Analysis

      TitleLot Number
      356780

      References

      Reference overview
      Cinatl, J., et al. 2003. Lancet 361, 2045.
      Tanahashi, T., et al. 2002. J. Steroid Biochem. Mol. Biol. 80, 441.
      Kondo, Y., and Takano, F. 1994. Biol. Pharm. Bull. 17, 759.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision18-January-2017 JSW
      SynonymsGlycyrrhizic Acid, NH₄+
      DescriptionA triterpenoid saponin, isolated from liquorice roots, that exhibits anti-viral and anti-tumor activities. Inhibits replication, adsorption, and penetration of severe acute respiratory syndrome-associated coronavirus (SARS-CV), presumably as a result of its ability to upregulate nitric oxide synthase activity. Also reported to hamper the growth of other viruses, including herpes virus. Shown to restore liver function in patients with hepatitis C virus (HCV). Also shown to inhibit 11β-hydroxysteroid dehydrogenase type 2 (11-HSD2).
      FormWhite to off-white solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number53956-04-0
      RTECSLZ6500000
      Chemical formulaC₄₂H₆₁O₁₆ • NH₄
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityAqueous NH₄OH (50 mg/ml)
      Storage +2°C to +8°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      Merck USA index14, 4505
      ReferencesCinatl, J., et al. 2003. Lancet 361, 2045.
      Tanahashi, T., et al. 2002. J. Steroid Biochem. Mol. Biol. 80, 441.
      Kondo, Y., and Takano, F. 1994. Biol. Pharm. Bull. 17, 759.