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454857 MAP Kinase Substrate, EGF-Receptor (661-681) T669 Peptide

454857
  
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      Overview

      Replacement Information
      Description
      OverviewSequence is based on the cytoplasmic domain of the EGF receptor and includes Thr669, a major phosphorylation site in cells stimulated by EGF, IL-1 and PMA. Poor substrate for MAP kinase kinase (MEK).
      Catalogue Number454857
      Brand Family Calbiochem®
      References
      ReferencesForce, T., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 11270. Williams, R., et al. 1993. J. Biol. Chem. 268, 18213. Haycock, J.W., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 2365. Bird, T.A., et al. 1991. J. Biol. Chem. 266, 22661.
      Product Information
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₁₀₁H₁₇₂N₃₀O₃₂
      Chemical formulaC₁₀₁H₁₇₂N₃₀O₃₂
      Hygroscopic Hygroscopic
      Sold on the basis of peptide contentY
      Applications
      Biological Information
      Purity≥97% by HPLC
      Physicochemical Information
      Peptide ContentY
      Peptide SequenceH-Lys-Arg-Glu-Leu-Val-Glu-Pro-Leu-Thr-Pro-Ser-Gly-Glu-Ala-Pro-Asn-Gln-Ala-Leu-Leu-Arg-OH
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      454857 0

      Documentation

      MAP Kinase Substrate, EGF-Receptor (661-681) T669 Peptide Certificates of Analysis

      TitleLot Number
      454857

      References

      Reference overview
      Force, T., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 11270. Williams, R., et al. 1993. J. Biol. Chem. 268, 18213. Haycock, J.W., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 2365. Bird, T.A., et al. 1991. J. Biol. Chem. 266, 22661.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision07-August-2008 RFH
      DescriptionPeptide sequence is based on the cytoplasmic domain of the EGF-receptor, including Thr-669, a major phosphorylation site in cells stimulated by EGF, IL-1, and PMA. Has been used at 1 mM in phosphocellulase assays for MAP kinase. Poor substrate for MAP kinase kinase (MEK).
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Chemical formulaC₁₀₁H₁₇₂N₃₀O₃₂
      Peptide SequenceH-Lys-Arg-Glu-Leu-Val-Glu-Pro-Leu-Thr-Pro-Ser-Gly-Glu-Ala-Pro-Asn-Gln-Ala-Leu-Leu-Arg-OH
      Purity≥97% by HPLC
      SolubilityH₂O (1 mg/ml) or aqueous buffers (1 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesForce, T., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 11270. Williams, R., et al. 1993. J. Biol. Chem. 268, 18213. Haycock, J.W., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 2365. Bird, T.A., et al. 1991. J. Biol. Chem. 266, 22661.